Posts in category: Uncategorized

You learn from your mistakes. At least, most of us have been told so. But science shows that we often fail to learn from past errors. Instead, we are likely to keep repeating the same mistakes.

Parkinson’s disease is an illness well known for its motor symptoms—tremor, stiffness, and slowness of movement. In a new paper published in The Journal of Neuroscience and featured on its cover, researchers at Yale School of Medicine have uncovered the biological mechanism behind another common, but less studied symptom—the loss of smell.

In the United States, an average of three people die every day waiting for a liver transplant, which resulted in nearly 1,200 lives lost in 2021. Liver allocation policy has undergone major modifications in the last 10 years. In a new study, researchers examined these policies, finding that despite the changes, geographic inequity persists. The authors recommend a more efficient and equitable way to allocate livers.

Mutating cells can prevent the spread of cancer by flipping themselves into a state of reduced activity called senescence. Cancer genes, however, can retaliate by reviving those cells so they can replicate again.

More than 70 people presenting at Singapore General Hospital’s emergency room with chest pain have been recruited to a new randomized controlled trial of a novel AI-based cardiac risk stratification tool that can rapidly and in real-time identify people whose chest pain is a sign of more serious trouble.

An obstetrician-gynecologist, or OB-GYN, accompanies patients through some of the most significant events of their lives.

A recent study by doctoral student Thinh Vu and Assistant Professor Sean Haley suggests that a universal health insurance program for people living with HIV/AIDS (PLHIV) in Vietnam could result in significant benefits.

Despite the increasing use of genomic sequencing in clinical practice, interpreting rare genetic mutations, even among well-studied disease genes, remains difficult. Current predictive models are useful for interpreting those mutations, but they are prone to misclassify those that do not cause diseases, contributing to false positives.

Published in Nature Microbiology, a study by researchers at the University of Copenhagen in Denmark has delved into the microbiota of patients with anorexia nervosa (AN) pathology and identifies the mechanistic interplay between restricted eating habits and how the gut microbiota’s natural response negatively accentuates the pathology. Additionally, fecal microbiota transplantation from AN cases to germ-free mice under energy-restricted feeding mirrored AN eating behaviors.

A new publication released today in The EMBO Journal identified a key protein in the molecular mechanism triggering neurogenesis in the hippocampus. They found that tight regulation of Yap1 activity is essential as dysregulation can cause tissue disruption seen in the early stages of brain cancer.