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UC Davis Health researchers have dosed the second participant in their clinical trial looking to identify a potential cure for HIV utilizing CAR T-cell therapy. The novel study uses immunotherapy. It involves taking a patient’s own white blood cells, called T-cells, and modifying them so they can identify and target HIV cells to control the virus without medication.

The blood–brain barrier (BBB) is a stringent, nearly impenetrable layer of cells that guards the brain, protecting the vital organ from hazards in the bloodstream such as toxins or bacteria and allowing only a very limited set of small molecules, such as nutrients, to pass through. This layer of protection, however, makes it difficult for researchers to study the brain and to design drugs that can treat brain disorders.

As autism diagnoses become increasingly common, health officials have wondered how many U.S. kids have relatively mild symptoms and how many have more serious symptoms, such as very low IQ and inability to speak.

Surgery to relieve leg pain and disability in some people with sciatica may be better than other non-surgical treatments, but the benefits are short-lived, lasting only up to 12 months, finds an analysis of the latest evidence published by The BMJ today.

Black adults with heart failure (HF) are more likely to die than white adults with the same condition. A new study published today in JAMA Cardiology that used the American Heart Association’s Get With The Guidelines—Heart Failure registry data to examine quality and outcomes at hospitals treating high proportions of Black patients with HF found that care is equitable, although areas for improvement remain to examine quality and outcomes at hospitals treating high proportions of Black patients.

Although many people admire the actions of people who engage in acts of extraordinary altruism, like altruistic organ donors, bone marrow donors, and heroes who rescue people from fires or accidents, they are also often mystified at what motivates these altruists to act.

Scientists in Melbourne have designed a new type of oral capsule that could mean pain-free delivery of insulin and other protein drugs.

Emerging adulthood (ages 19 to 25 years) is a developmental phase that is marked by increased mental health conditions, especially depression and anxiety. Online peer emotional support is one mental health intervention that has demonstrated positive implications for the psychological well-being of emerging adults in current research literature.

A retrospective study of temperatures in the province of Barcelona reveals that low temperatures increase the risk of going on a period of sick leave, due in particular to infectious and respiratory diseases.

A drug called teriflunomide may delay first symptoms for people whose magnetic resonance imaging (MRI) scans show signs of multiple sclerosis (MS) even though they do not yet have symptoms of the disease. The preliminary study, released April 19, 2023, will be presented at the American Academy of Neurology’s 75th Annual Meeting, being held in person in Boston and live online from April 22-27, 2023.