Fasting triggers autophagy in our body. The body switches on the waste disposal system in the cells and gains new energy. Researchers at the Max Planck Institute for Metabolism Research in Cologne have now shown in mice that the brain plays a decisive role in this process.
Cocktail of modified antibodies found to provide strong effect against SARS-CoV-2
Is it possible to improve the antibodies that the body produces to fight SARS-CoV2? In a study led by researchers from Lund University in Sweden, this was investigated by redesigning antibodies and combining them against the virus. The modified antibodies have been tested in human cells and with mice.
Clinical trial shows tumor-starving drug improves survival of mesothelioma
Peter Szlosarek, Professor of Medical Oncology at Queen Mary’s Barts Cancer Institute, presented his team’s results from the ATOMIC-Meso clinical trial in partnership with Polaris Pharmaceuticals, Inc., at the American Association for Cancer Research Annual Meeting. The findings show that the new drug, called ADI-PEG20, extends the median survival of patients compared with current standard treatment. This moves the drug closer to final approval by the US Food and Drug Administration (FDA), an achievement that would represent the first such approval of a new chemotherapy drug for this disease in 15 years.
Study of interleukin-6 impact on organoids shows increase in radial glia cells
A team of medical researchers at the University of Tübingen’s Hertie Institute for Clinical Brain Research in Germany has found that exposing organoids at a certain stage of growth to interleukin-6 leads to an increase in radial glia cells, which may provide a hint as to why pregnant women who experience infections are more likely to deliver a child who develops autism.
Predicting epidemics isn’t easy: Researchers have created a global dataset to help
The world has recently seen a number of high-profile cross-border disease outbreaks and pandemics. The COVID pandemic and multi-country Mpox (monkeypox) outbreaks are just two examples.
Public health care fared better than the private sector in the coronavirus pandemic, study finds
Publicly funded health care systems in developed countries fared better in terms of excess mortality and case fatality associated with COVID-19 than private sector health care. A study compared the performance of health care systems in 43 developed countries during the coronavirus pandemic.
How electricity can heal wounds three times faster
Chronic wounds are a major health problem for diabetic patients and the elderly—in extreme cases they can even lead to amputation. Using electric stimulation, researchers in a project at Chalmers University of Technology, Sweden, and the University of Freiburg, Germany, have developed a method that speeds up the healing process, making wounds heal three times faster.
Clarify on multiple gov’t spokespersons, Kampyongo asks Secretary to Cabinet
By NATION REPORTER
THE opposition has called on government to clarify the role of multiple spokespersons in government who are responding in un-coordinated and un-procedural manner to political issues.
Opposition Chief Whip Stephen Kampyongo has challenged Secretary to the Cabinet Patrick Kangwa to call is officers to order to enforce discipline in the manner that government responses are generated by officers whose designation did not merit them to speak on behalf of rightful authorities.
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Researchers find new clues to potential cause of OCD
QIMR Berghofer researchers are a step closer to solving what causes obsessive-compulsive disorder, after discovering changes in how distinct brain regions communicate. This important finding could guide the development of more targeted and effective treatments for this debilitating condition impacting thousands of Australians.
Research finds removing ovaries at benign hysterectomy carries health risks
An emulated target trial of more than 140,000 women in Denmark found that removing the ovaries at benign hysterectomy was associated with increased risk for cardiovascular disease in younger women and cancer in older women at low risk for ovarian cancer. These findings support current recommendations for preserving ovaries in premenopausal patients. The findings are published in Annals of Internal Medicine.