Cart is empty Many cancers are caused by fusion oncoproteins, molecules that aberrantly form when a rearrangement of DNA results in parts of two different proteins being expressed as one. Several fusion oncoproteins spontaneously form condensates inside cells that promote cancer development.
Widespread naloxone distribution not enough to impact overdose death rate: Study
The highest ever number of opioid-related overdose deaths in the United States was recorded in 2020 at 68,630, a 68% increase in just two years. Naloxone is a medicine that can rapidly reverse an opioid overdose, but a new study out of the University of Cincinnati finds that widespread community distribution of naloxone through a take-home naloxone (THN) program did not significantly impact the median monthly opioid overdose rates.
Research finds Paxlovid and Legevrio reduced COVID-19 hospitalization and death
New Cleveland Clinic-led research shows commonly used COVID-19 anti-viral drugs Paxlovid (nirmatrelvir) and Lagevrio (molnupiravir) reduce risk of hospitalization and death in high-risk patients with mild disease, even with omicron subvariants.
Immune checkpoint blockade prior to surgery promising in multiple cancer types, finds study
Treating cancer with immunotherapies known as an immune checkpoint blockade (ICB) prior to surgery (so-called neoadjuvant immunotherapy) has been a rapidly growing area of research, but the scientific community is just scratching the surface of what is possible, according to a review article co-authored by several current and former investigators from the Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Kimmel Cancer Center.
UPND’s mishandling of economy irks EFF
By NATION REPORTER
ECONOMIC Freedom Fighter’s (EFF) president Kasonde Mwenda is disappointment with the alleged continued fiscal and economic mismanagement by the UPND government.
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Study reveals more depression in communities where people rarely left home during the COVID-19 pandemic
Higher levels of depressive symptoms have been reported during the COVID-19 pandemic compared with other times in history, and as much as three times higher than prior to the pandemic. A team led by investigators at Massachusetts General Hospital (MGH) has found that social isolation may have been a contributing factor. Their findings are published in JAMA Network Open.
Antibiotic shows effectiveness against deadly staph infections
An antibiotic that has shown effectiveness for bacterial pneumonia also appears successful in fighting methicillin-resistant staph infections, reports a team led by Duke Health.
Type of cellular stress involved in Parkinson’s disease destroys more neurons when it occurs at night, study finds
Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson’s disease. However, the link between biological rhythm and neuronal degeneration remains unclear. A team from the University of Geneva (UNIGE) has investigated the destruction of neurons at different times of the day, using the fruit fly as a study model.
FRA pays out K1bn to farmers
By BUUMBA CHIMBULU
THE Food Reserve Agency (FRA) has announced that over K1 billion has been paid to farmers that delivered A-grade white maize during this year’s on-going crop-marketing season.
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New study provides evidence for more effective brain-based treatment of chronic back pain
A new study in JAMA Network Open may provide key answers to how to help people experiencing chronic back pain.