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Researchers at Baylor College of Medicine have developed a new compound called d16 that can reduce tumor growth and overcome therapeutic resistance in mutant p53-bearing cancers in the lab. The findings, published in the journal Cancer Research Communications, open opportunities for new combination therapies for these difficult-to-treat cancers.

People are constantly learning from others without even being aware of it. Social learning avoids laborious trial and error; the wheel does not have to be reinvented each time. But where does this ability come from, which forms the basis of cultural learning and consequently for the evolutionary success of the human species?

Children of color and those from families with low incomes are disproportionately exposed to neurotoxic chemicals, resulting in greater harm to brain development and more developmental delays, according to a new review of five decades of studies co-led by a University of Maryland researcher.

A University of Texas at Arlington research team found that foreign-born women of Middle Eastern and North African (MENA) descent are 2.5 times more likely to have an undiagnosed case of Alzheimer’s disease and related dementias (ADRD) compared to U.S.-born white women.

Don’t worry about your hips or knees as you age. Arthritis in those joints isn’t inevitable. Keep doing the activities you enjoy. Those hopeful words come from Rafael Sierra, M.D., an orthopedic surgeon at Mayo Clinic specializing in hip and knee reconstruction. Dr. Sierra says there is no need to curtail your activities out of fear that you’ll wear out those joints as you age and need joint replacement.

COVID-19 was the third leading cause of death in 2022, accounting for more than 1 in 20 deaths (9,859 of 190,939 deaths), according to figures released today (Sept. 27) by the Australian Bureau of Statistics (ABS).

For mothers who experience high stress during their pregnancy, prenatal COVID-19 infection may be associated with an increased risk for impaired attention and delayed socioemotional and cognitive functioning in their infants, according to a small study published in Pediatric Research.

Having a chronic illness is a great deal of work, communication researchers have long known. But having an illness that is stigmatized, not well understood or not perceived as a priority by clinicians is uniquely burdensome for many women, who find themselves struggling to establish both the legitimacy of their medical problems and their credibility with clinicians, family members and friends, a recent study suggests.

Most contraceptive pills are based on a cycle of taking the pill for 21 days, and then stopping the pill for 7 days. Now researchers have found that women’s mood worsens during the 7 pill-free days. This work will be presented at the ECNP congress in Barcelona on October 8. The research is also published in JAMA Network Open.

A new imaging agent, 68Ga-ABY-025, can predict early metabolic response to human epidermal growth factor receptor 2 (HER2)-targeted treatment in HER2-positive metastatic breast cancer patients, according to new research published in the Journal of Nuclear Medicine. By providing whole-body quantification of HER2 expression, 68Ga-ABY-025 PET/CT can play a valuable role in treatment planning and could spare patients from unnecessary drug-related side effects.