In recent years, cancer immunotherapies, represented by immune checkpoint blockade (ICB), have been highly successful and have become an important basis for the future treatment of cancers. However, the absence of tumoral killer T cells and the complexity of tumor microenvironment can both affect the immunotherapeutic efficacy. Therefore, it is urgent to develop novel anti-tumor agents that can effectively promote effector T cell infiltration in tumors.
Researcher inhibits flu viruses by blocking the enzyme that cleaves off virus particles
A flu virus could cause a pandemic, and we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12.
Ndola Man 35, defiles 6 year old
A 35-YEAR-OLD man has defiled a six years old girl in Kaloko compound, Ndola district in the Copperbelt province. Â
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Commonly used muscle-building dietary supplements are under regulated in Canada, finds study
A new policy analysis, published in the journal Performance Enhancement & Health, highlights several gaps in current Canadian policy regulating muscle-building dietary supplements. Muscle-building dietary supplements, including whey protein, creatine monohydrate, and amino acids, are used based on purported benefits to muscular growth and recovery. These products are regulated by the Natural Health Products Regulations under Health Canada.
Red Cross appeals for donors during national blood shortage
The American Red Cross said Monday that it urgently needs blood donations because the national blood supply has dropped nearly 25 percent since early August.
Socializing found to boost mood more than screen time
It turns out people might prefer social interactions over their smartphones, but that doesn’t mean they’re going to stop scrolling.
‘It’s not fair!’ Kids grumble and complain for a reason, here’s how to handle it
Parents have no doubt heard all the classic grumbles from children and teenagers. From “It’s not fair!” to “Not spinach again!” and our personal favorite, “Why do ‘I’ have to do all the work?”
Women’s pain is often not believed—here’s how to make your voice heard when seeking help
When you go to the doctor, you expect they’ll listen to your concerns and help fix whatever problem you may be experiencing. But many women, especially those suffering with chronic pain conditions, find the opposite is true. This can make it difficult for women to get the treatment they need.
Q&A: How evasive and transmissible is the newest omicron offshoot, BA.2.86, that causes COVID-19?
The latest variant, or sublineage, of SARS-CoV-2 to emerge on the scene, BA.2.86, has public health experts on alert as COVID-19 hospitalizations begin to rise and the new variant makes its way across the globe.
Even in the most depressed county in America, stigma around mental illness persists
Sitting on a bench laughing with a co-worker during a morning smoke break, Debra Orcutt quickly raises her hand when asked if she knows anyone dealing with depression.