Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer’s disease is safe

Alzheimer’s disease is the most common cause of dementia that affects more than 6.5 million Americans, according to the Alzheimer’s Association. To find effective treatments and slow the progression of this debilitating disease, researchers have made much progress in developing new drugs that target beta-amyloid plaques, one of the hallmarks of Alzheimer’s disease.

Online AI-based test for Parkinson’s disease severity shows promising results

An artificial intelligence tool developed by researchers at the University of Rochester can help people with Parkinson’s disease remotely assess the severity of their symptoms within minutes. A study in npj Digital Medicine describes the new tool, which has users tap their fingers 10 times in front of a webcam to assess motor performance on a scale of 0–4.

HEED ADVICE

GOVERNMENT must get to grips with the self-created incumbrances in the agriculture sector which is putting the country’s food security at risk.

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Synthetic heparanase inhibitors: Research team develops alternative method for the treatment of herpes

Herpes is not only unpleasant but it can, in some cases, also have dangerous complications and life-threatening consequences. In the journal Angewandte Chemie, a research team has now introduced a completely new approach for treating herpes. Their method is based on the inhibition of an enzyme that is needed for the release of newly formed virus particles from infected cells.

New research reveals close connection between cognitive flexibility and neurogenesis

The ability to shift from one type of cognitive problem-solving strategy to another when the circumstances change, called cognitive adaptability or flexibility, is an essential function for humans. When this ability is diminished—whether by aging, disease, trauma, or environmental exposure—mental behavior becomes more inflexible and a person has difficulty adapting to new cognitive demands and remains stuck in the previous way of thinking.