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Medicines that are based on mRNAs and proteins—particularly vaccines and antibodies—are time-intensive and costly to make. The challenge is in producing the necessary mRNAs and proteins in large enough amounts at low cost.

The bones of the face and skull can be affected due to a wide range of conditions, including cleft palate defects, traumatic injuries, cancer, and bone loss from dentures. Although bone replacements are routinely used to regenerate the missing tissue, they are vulnerable to bacterial infection. In a new study, researchers investigated whether manuka honey, made from tea trees, can be used to resist bacterial infection and promote bone growth.

POLICE in Chambishi have detained a truck driver whose stray bullet hit and injured two women who were in makeshift restaurants selling food when one of the several shots he fired to scare criminals hit and injured the women.
Copperbelt Police Commissioner Peacewell Mweemba said the incident occurred yesterday around 11: 30 hours along the Chambishi Copper Smelter (CCS) road near Puma Filling Station in Chambishi in which an anonymous call was received by Police that women were shot at and injured after a truck driver fired gunshots
Mr Mweemba said the two victims who were rushed to Chambishi Government Clinic, have been identified as Treazer Kamwendo Malichi aged 37 of house number B- 282 Kabanda Area Zambia Compound Chambishi, a business lady, who sustained a gunshot wound on her left knee
The other victim was identified as Getrude Chilumba, aged 27 of the same address, who sustained a gunshot wound below her left shoulder.
Mr Mweemba said there are booths and makeshift restaurants alongside CCS Road near Puma Filling Station and along this road, criminals usually jump onto trucks to steal whatever cargo or goods they find on the trucks, especially when trucks stop or slow down. 
He said on February 20, 2023, at around 12:30 hours, a truck driver namely identified a Trust Sakala aged 56 of house number 108/75 Kanyama West Lusaka, driving a freightliner truck and trailer reg No ALE 4791 and ABZ 9111T belonging to AM Transport Company, was going towards CCS from Kitwe-Chingola road.
“The truck driver stopped along the road to pick up his fellow driver, who was going to CCS. Immediately, a group of criminals jumped onto the trailer and started pulling the tents. He tried to stop them, but the criminals started throwing stones at him. It was at this point that the driver got his pistol and fired several shots towards the group to scare them, forcing the group to run away.
“However, it was discovered that two females who were in one of the makeshift restaurants doing their business of selling food, were caught by stray bullets, and got injured, Ms Treazer Kamwendo Malichi and Ms Getrude Chilumba, aged 27 of the above address (B 282) who sustained a gunshot wound below her left shoulder,” Mr Mweemba said
He said Police rushed to the clinic and found victims being attended to and later referred to Kitwe Teaching Hospital (KTH) where their condition for both was stable. 
“Medical report forms were issued. The truck driver is in police custody for unlawful wounding pending further investigations, while the pistol Luger, serial No C6878 with 13 rounds of ammunition has been confiscated,” he said

A long-acting antiretroviral treatment (LA-ART) given every four to eight weeks, and delivered with comprehensive support services, suppressed HIV in people who were previously not virologically suppressed. This is according to an ongoing demonstration study of 133 people with HIV in San Francisco, funded by the National Institutes of Health. The study focused on reaching people who have historically had decreased access to antiretroviral therapy (ART), including people experiencing housing insecurity, mental illnesses, and substance use disorders. The study findings indicate that long-acting injectable ART can benefit people who face many treatment barriers and are historically underserved.

In 2019, the World Health Organization formally recommended the drug dolutegravir (DTG) as the preferred antiretroviral therapy (ART) for people living with HIV in low and middle-income countries (LMICs), citing that it is more effective and tolerable, less costly, and less prone to developing drug resistance than the previously recommended first-line treatment efavirenz (EFV).

Breathing practice as well as gradual aerobic exercise may help improve concussion symptoms in teens experiencing slow recovery, according to a preliminary study released today, February 21, 2023, that will be presented at the American Academy of Neurology’s 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023. The study found that while the two therapies are each beneficial separately, when combined they resulted in even greater improvement in thinking and memory skills, depression and mood.

A new Slovenian population-scaled, school-based study shows that by providing additional physical education lessons to young children is effective in preventing childhood obesity, according to findings published in Obesity, The Obesity Society’s (TOS) flagship journal.

A monthly vaginal ring containing the antiretroviral drug dapivirine—an HIV prevention method that has been approved in several African countries and recommended by the World Health Organization (WHO) –appears to be safe when used during breastfeeding, suggest results of a Phase IIIb open-label study presented today at the Conference on Retroviruses and Opportunistic Infections (CROI 2023) in Seattle.

A fast-dissolving insert being developed as an “on-demand” HIV prevention method was found to be safe and well-tolerated in the first study of its use rectally. The results, which were presented today at the Conference on Retroviruses and Opportunistic Infections (CROI 2023) in Seattle, also found the insert delivered high levels of the anti-retroviral drugs tenofovir alafenamide (TAF) and elvitegravir (EVG) to rectal tissue and fluid, with very little drug circulating elsewhere in the body, and results of laboratory tests suggesting the insert could potentially provide protection for up to three days after use.

BUILDING contractor has told the Lusaka Magistrate Court that he signed a contract with former Deputy Inspector General of Police Charity Masambo Katanga amounting to K1.8 million for purposes of building her a flat.
However, Mr. Osman Dodia, 61, of Quorum Construction Ltd in cross-examination submitted that, there was nothing unusual in building Ms. Katanga a flat because everything went well as the right procedure was followed.
In this matter, Katanga is facing one count of possession of property reasonably suspected of being proceeds of crime contrary to section 71(1) of the forfeiture of the Proceeds of Crime Act No. 19 of 2010 of the laws of Zambia.
Mr. Dodia testified that he made a first contract with the sum of K1.4 million (K1.448.137.98) and later the cost was elevated to K1.8million.
“The agreement offer was signed by both parties but some changes where being made as we moved on and contract sum was being affected. The overall cost for the contract reached k1.8 million,” he said.
Mr. Dodia narrated that he completed the project and handed it over to the client.
“I was paid well and in time, there was a cordial relationship between us and madam Katanga,” he said.
According to the Drug Enforcement Commission, cash money amounting to K1, 522,005.00 in her company was seized reasonably suspected to be proceeds of crime.
It is alleged that Katanga on dates unknown between January 1, 2017 and June 6, 2022 in Lusaka with other person’s unknown did possess 10 Higer buses with Motor Vehicle registration numbers BAF 8518 ZM, BAF 5119 ZM, BAG 8558 ZM, BAG 8559 ZM, BAG 8733 ZM, BAJ 2476 ZM, BAJ 2590 ZM, BAJ 2919 ZM, BAJ 2590 ZM, BAJ 2919 ZM, BAV 2931 ZM and BAL 9126 ZM respectively, all together valued at k26,282,770.00 property reasonably suspected of being proceeds of crime, the charge she recently denied.
Trial continues today.