FGFR3-TACC3 represents an oncogenic fusion protein frequently identified in glioblastoma, lung cancer, bladder cancer, oral cancer, head and neck squamous cell carcinoma, gallbladder cancer, and cervical cancer. Various exon breakpoints of FGFR3-TACC3 have been identified in cancers.
Understanding the value of a physician’s intuition when assessing risk factors for surgery
Preoperative surgeon intuition is an independent predictor of 30-day postoperative complications; however, when compared to the standard risk calculator derived from the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP), its predictive power isn’t as strong, according to a study published in the Journal of the American College of Surgeons (JACS).
Q&A: Why you should publish negative data
As a bachelor student of Bio-Pharmaceutical Sciences, Femke Vlaswinkel wrote a research proposal she was allowed to carry out in her master’s BPS. Femke subsequently graduated with honors. Her research was published in the journal Scientific Reports, she won an award from the Dutch Pharmacy Society (KNMP) and she was invited to write an article about it for a pharmaceutical journal.
New study finds millions in US missed cancer screening during second year of COVID-19 pandemic
According to a new, nationwide study led by researchers at the American Cancer Society (ACS), millions of people in the United States continued to miss critical cancer screening tests during the second year of the COVID-19 pandemic.
Study finds air pollution exposure linked to Parkinson’s risk, identifies US hot spot
Living in areas of the United States with higher levels of air pollution is associated with an increased risk of Parkinson’s disease, according to a preliminary study released today, February 23, 2023, that will be presented at the American Academy of Neurology’s 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023.
A single session of hypnosis and mindfulness meditation may be useful for managing acute pain
Researchers compared the immediate effects of hypnosis, mindfulness meditation, and Christian prayer on pain intensity and tolerance. The results suggested that a single session of hypnosis and mindfulness meditation, but not prayer, may be useful for managing acute pain, with hypnosis being slightly more useful.
New promising targeted drug for a rare leukemia
Targeted drugs have been developed to supplement chemotherapy in the treatment of cancer. These drugs only affect cancer cells, leaving healthy cells alone. Venetoclax is a new targeted therapy option for the treatment of acute myeloid leukemia (AML). Venetoclax was recently granted marketing authorization in Finland.
Phase 3 trial finds oral empagliflozin provides safe glycemic control in children with type 2 diabetes
Type 2 diabetes is a chronic disease in which the body does not produce enough of the hormone insulin, which regulates blood sugar, while cells in the muscle, fat and digestive system simultaneously become less sensitive to it, absorbing less sugar from the blood stream. The condition results in high blood sugar levels, which over time can cause damage to the heart, nerves, eyes, and kidneys, as well as delay wound healing and diminish cognitive function. Controlling blood sugar (glycemic levels) through medication is critical to staving off these many complications.
Researchers link supplement to reduced biomarkers of Alzheimer’s in the brain
For the first time, a researcher at the University of Delaware College of Health Sciences in collaboration with a team at the National Institute on Aging, a division of the National Institutes of Health, has determined that the naturally occurring dietary supplement known as nicotinamide riboside (NR) can enter the brain.
First detailed description of Helicobacter-infected individuals
The first detailed description of the microbiota and immune cells among asymptomatic Helicobacter pylori-infected individuals has been published by researchers at Karolinska Institutet. The results of the study will be instrumental to understanding the complex microbiome and immunity network and provide new insights for asymptomatic Helicobacter pylori infection.