In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most common signaling molecules, glutamate, opens a channel and allows a flood of charged particles to enter. The finding, which resulted from a study led by Johns Hopkins Medicine researchers, could advance the development of new drugs that block or open such signaling channels to treat conditions as varied as epilepsy and some intellectual disorders.
Clinical trials show new antibody therapy offers long-lasting HIV control without daily medication
If the past four decades have taught us anything about HIV, it’s to adjust our expectations—despite enormous progress in controlling the virus, no treatment can yet completely eradicate HIV once it has taken hold. But promising results from a recent clinical trial suggest that broadly neutralizing antibody therapy (bNAbs) may be able to accomplish the next best thing.
Updated American Academy of Neurology position statement issued on seizures, driving licensure
In a position statement issued by the American Academy of Neurology and published online March 12 in Neurology, an updated consensus is presented relating to seizures, driving licensure, and medical reporting.
Immunization program for babies slashes RSV hospital admissions
An Australian-first study demonstrating the effectiveness of a new immunization against respiratory syncytial virus (RSV) for babies found it to be almost 90% effective in reducing hospitalization rates and helped more than 500 WA families avoid a hospital stay.
Nasal protein could aid in early COPD detection
Early diagnosis of COPD, chronic obstructive pulmonary disease, increases the quality of life of the patient and the efficacy of available treatments. Researchers at Karolinska Institutet have now shown that material from nasal lavage provides a basis for assessing COPD. The study, which has been published in the Journal of Allergy and Clinical Immunology, could lead to a simple diagnostic method for early assessment of COPD.
Liver disease patients dramatically improve thanks to new approach
Damaged human livers can repair themselves. Even livers badly scarred from excessive alcohol use, including alcohol-related hepatitis and cirrhosis, have the potential to improve with a treatment plan that includes medication, abstinence, and emotional support.
AI can serve up ideas for healthy meals in a snap, but they come with a side of caution
For anybody who’s struggled to pull together a grocery list or plan a week of family meals, the promise of assistance from artificial intelligence is downright appetizing.
Many women undergo annual mammography, despite biennial screening recommendations
A high proportion of women seem to undergo mammography screening every year, despite recommendations for biennial screening, according to a research letter published online March 25 in the Annals of Internal Medicine.
Everyday physical activity does not slow bone loss during menopause, finds study
According to a recent study from the University of Jyväskylä, Finland, the impacts of everyday physical activity do not attenuate the accelerated hormonal bone loss that occurs during menopause. Effective bone-loading impacts are rare in everyday life. Future research should explore whether more targeted exercise can slow menopausal bone loss. The study suggests that impacts accumulated during everyday life are not sufficient to slow hormonal bone loss during menopause.
Understanding Australian bat lyssavirus: Risks and safety measures
Last week, Queensland Health alerted the public about the risk of Australian bat lyssavirus, after a bat found near a school just north of Brisbane was given to a wildlife caregiver group.