Cart is empty An interdisciplinary collaboration 10 years in the making used a materials science approach to “fingerprint” the calcium mineral deposits known as microcalcifications that reveal pathological clues to the progression of breast cancer and potentially other diseases.
Study: Metformin’s impact on aging and longevity through DNA methylation
A new research paper was published in Aging, titled “Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity.”
Parkinson’s disease patients experience significant reduction in symptoms with non-surgical focused ultrasound treatment
Patients with Parkinson’s disease achieved a significant improvement in their tremors, mobility, and other physical symptoms after having a minimally invasive procedure involving focused ultrasound, according to a new study today published in the New England Journal of Medicine.
Second generation gene therapy for alpha 1-antitrypsin deficiency
Researchers report on the safety of a gene therapy to treat the common autosomal recessive hereditary disorder alpha 1-antitrypsin (AAT) deficiency in a new article in Human Gene Therapy.
Terminal sterilization of oligonucleotide drug products
A new report, coauthored by several major pharmaceutical companies, reviews the current state of sterile oligonucleotide drug product processing. The article, which provides recommendations to aid in the evaluation and development of terminal sterilization processes, is published in Nucleic Acid Therapeutics.
Mapping unknown territory in the zebrafish brain to gain insight into neural structure
When one travels through rough terrain, maps come in handy. They also help researchers to study the complex organization of the brain. Scientists at the Max Planck Institute for Biological Intelligence have created a new set of maps for the zebrafish brain. They determined the activity of hundreds of genes with single-cell resolution and assembled the maps into an interactive atlas. The online resource supports researchers in finding their way around the brain of this vertebrate and provides new insights into neural structure and function.
Effectiveness and safety of osteopathic treatments in relation to pain in the musculoskeletal system
Chronic low back pain and other chronic back problems are the most common health problems in Austria: it is estimated that almost half of all Austrians suffer from chronic neck, low back or back pain, which is extremely burdensome in everyday life and reduces the quality of life.
New study reveals how lung cells protect themselves against RNA viral infection
A new University of California, Irvine-led study uncovers how a protein called APOBEC3B could protect cells against many different types of RNA viruses like respiratory syncytial virus (RSV), SARS-CoV2, influenza virus, poliovirus and measles, helping to prevent disease. The study was published in Nature Communications.
New analysis could help forecast malaria outbreaks
As with COVID, public health agencies around the world have struggled to predict which communities will be hit the hardest with malaria, a life-threatening disease that infected an estimated 247 million people in 2021. A new Stanford-led study done in collaboration with local scientists and health care experts in Madagascar paves the way to using easily obtainable data to accurately predict malaria outbreaks in communities.
Study finds computer-based intervention is cost-effective at reducing binge drinking among adolescents
A computer-based intervention associated with reduced binge drinking episodes among high school students could yield a cost savings of eight thousand euros, according to a Spanish study published in Alcohol: Clinical and Experimental Research. The study found the computer-based intervention cost-effective, resulting in societal savings of €8,000 for each binge drinking episode averted. Computer and web-based interventions can potentially reach a far larger number of students than face-to-face screening and intervention.