Posts in category: Uncategorized

Thanks to machine learning algorithms, short pieces of DNA floating in the bloodstream of cancer patients can help doctors diagnose specific types of cancer and choose the most effective treatment for a patient.

Treatment with modern antidepressants may help prevent patients with bipolar disorder from relapsing into a depressive episode, according to an international clinical trial led by researchers at the University of British Columbia.

THE monthly review of fuel still remains a challenge for local businesses, says the Centre for Trade Policy and Development (CTPD).

Teens who have been bullied by their peers, or who have considered or attempted suicide, may be more likely to have more frequent headaches than teens who have not experienced any of these problems, according to a study published in the August 2, 2023, online issue of Neurology. The study does not prove that bullying or thoughts of suicide cause headaches; it only shows an association.

Patients who live in less affluent neighborhoods and those from underrepresented racial or ethnic groups are less likely than others to receive specialized care for dementia, including Alzheimer’s disease, a new study from Washington University School of Medicine in St. Louis indicates.

A new research perspective titled “Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?” has been published in Aging.

Amyloid deposition is a hallmark of neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). The deposition process is described as a sigmoidal curve in which the misfolded proteins assemble into oligomers before fibril elongation. This dynamic process is accompanied by the misfolded monomer with more α-helix formed into abundant crosslinked β-sheet structure. Targeting the toxic accumulation may represent a promising strategy to slow or prevent disease initiation.

Metastases and resistance to chemotherapy are the main causes of treatment failure and mortality in cancer patients. Epithelial-mesenchymal transition (EMT), a process by which cancer cells detach from their neighboring cells and acquire invasive properties, plays a key role in the formation of metastases and the development of resistance to anti-cancer treatments. To date, there is no therapy targeting EMT in cancer.

Hydrocephalus, commonly known as fluid or water on the brain, can occur in the womb or be caused by hemorrhage, tumors, trauma or infection. The “water” in this case is an excess of cerebrospinal fluid in the brain’s cavities. As fluid accumulates, pressure builds in the brain, compressing and damaging tissues. This often leads to physical and behavioral changes like headache, seizures and sluggishness, among many others, and it can be fatal.

One of the beneficial gut bacteria residing in the human gut, which normally cannot survive in an environment with oxygen, can now be made oxygen-tolerant. This is a key finding in the development of future probiotic treatment that is now being explored to improve glucose control in individuals with prediabetes.