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A new study in Gastroenterology identifies how certain proteins in the immune system interact and lead to organ rejection. The study, which involved experiments on mice and human patients, uncovered an important communication pathway between two molecules called CEACAM1 (CC1) and TIM-3, finding that the pathway plays a crucial role in controlling the body’s immune response during liver transplantation.

Dehydration brings lots of risks—including urinary tract infections (UTIs).

Combining two types of heart scan techniques could help doctors to detect the deadly heart condition hypertrophic cardiomyopathy (HCM) before symptoms and signs on conventional tests appear, according to a new study led by UCL researchers.

Research conducted at the University of São Paulo (USP) in Brazil shows that SARS-CoV-2, the virus that causes COVID-19, can infect liver cells (hepatocytes), stimulating glucose production and leading to a condition similar to diabetes (hyperglycemia) in hospitalized patients, even if their blood sugar level was normal before they were admitted to hospital.

The formation of the country’s first emergency department for the over 80s led to a significant decrease in time spent in A&E—according to research from the Norfolk and Norwich University Hospital (NNUH) and University of East Anglia (UEA).

Diabetic kidney disease (DKD) is a major microvascular complication of type 2 diabetes mellitus (T2DM), causing irreversible kidney damage and poor prognosis for patients. Early monitoring and screening of renal injury are necessary for patients with T2DM, particularly for those with a long disease course.

The longest nerve in the human body starts in the brain and meanders its way down the neck and into the chest, where it splits into separate branches, winding its twisting tendrils to touch each internal organ. Known as the “information superhighway” and aptly named from the Latin word meaning “wanders,” the vagus nerve is a bundle of fibers responsible for the parasympathetic nervous system: digestion, heart rate, breathing.

Scientists have long used community advisory boards to engage communities and provide feedback on studies, but this model has limitations. Now, researchers from The Wistar Institute are sharing how a more inclusive model for community engagement can lead to deeper insights and greater community participation in HIV research. The community engagement group, or CEG model, is composed of a three-part structure with a community advisory board (CAB), community nonprofit organization, and researchers.

Coronary heart disease is the leading cause of adult death worldwide. In many cases, quantifying left ventricular ejection fraction (LVEF)—or how much blood the left ventricle pumps out with each contraction—is critical to optimize decision-making and treatment decisions, particularly for acute coronary syndromes like heart attacks or unstable angina.

ZAMBIA is expected to reach a debt restructuring deal with its international bondholders by the time the International Monetary Fund (IMF) undergoes a second review of its rescue loan programme with the country later this year, an IMF official said on Friday.