Cart is empty A new boron agent drastically improves the effectiveness of boron neutron capture therapy for glioblastoma, demonstrate researchers at Tokyo Tech. The agent is selectively absorbed by brain tumor cells, exhibits enhanced blood retention, and can be administered at low doses. Experiments on cell cultures, mice, and rats show promising results, highlighting the potential of the novel agent for radiotherapy.
Stimulant therapy for ADHD in teens doesn’t increase risk of cocaine or methamphetamine use later: Study
Many parents whose kids take prescription stimulants like Ritalin to treat ADHD worry that it could lead to illicit drug use later.
Musical rhythms can improve language processing of children with developmental language disorder, study
A new study led by a Western Sydney University researcher has found that musical rhythms can help children with speech and language processing difficulties in finding their voice by improving their capacity to repeat sentences they just heard.
Poignant photo project reveals all we lost in lockdown
Laptops and schoolwork on kitchen tables, a deserted playground, face masks on a washing line, an empty church, a walk in the woods.
Estrogen and PARP inhibitor combination for advanced ER+ breast cancer shows promise in preclinical models
Advanced estrogen receptor-positive (ER+) breast cancer can be especially difficult to treat. A new study by researchers at Dartmouth Cancer Center led by Todd W. Miller, Ph.D., shows promise in using a combination of estrogen and a PARP inhibitor (a drug that suppresses DNA damage repair), to treat this type of cancer.
Biomaterial-delivered one-two punch boosts cancer immunotherapy
Cancer immunotherapy has brought major improvement in patient survival and quality of life, especially with the success of adoptive T cell and immune checkpoint inhibitor therapies. Unfortunately, in contrast to different blood cancers, the effectiveness of adoptive T cell therapies in the treatment of solid tumors, which comprise about 90% of all tumors, has been very limited because of several formidable barriers.
Researchers pinpoint protein tied to drug resistance in patients with lung cancer
Cancer therapies that target specific genetic abnormalities in tumors have revolutionized treatment possibilities over the past two decades. While quality of life and survival are improved with targeted therapies, relapse is common due to the evolution of new tumor cells that are resistant to the targeted therapy.
Basic levels of sickle cell care needed immediately; global mortality may be much higher than recorded
Reducing the burden of sickle cell disease (SCD) requires substantial financial and political commitment to improving dataccollection, diagnosis, treatment and training. Doing so will positively impact the lives of millions of patients and families worldwide—says a new Commission published in The Lancet Haematology journal.
New findings may explain why mRNA vaccines provide limited protection against omicron
Vaccination protects against severe COVID-19 but not against infection. Researchers at Karolinska Institutet and Danderyd Hospital now show that protection against infection with the new omicron variants is linked to mucosal IgA antibodies, which are not induced by vaccination. These are the findings of two studies recently published in The Lancet Infectious Diseases, and The Lancet Microbe, and could explain the limited protection by currently available vaccines against infection.
Scientists develop new gene delivery and immune cell engineering technology for future cancer cell therapies
Scientists at Yale have developed a new gene delivery and immune cell engineering technology with the potential to advance cell therapies for cancer and other diseases.