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A new paper from MUSC Hollings Cancer Center researchers is helping to reveal the “rules” for engineering chimeric antigen receptor (CAR) Tregs.

Bone is a highly vascularized tissue, and the link between angiogenesis -blood vessel formation- and bone healing has long been discussed by the scientific community, with several studies describing the impairment of bone healing because of lack of or diminished angiogenesis. Traditional approaches like grafting often result in complications due to an inadequate vascular supply to implants, leading to poor integration and necrotic tissue.

The economic impact of dental caries (tooth decay) is disproportionately higher in the most deprived groups, with estimated per-person costs of approximately £18,000 in the UK that could be dramatically reduced with targeted preventative measures, found new research.

An international research team, including researchers at Karolinska Institutet, has mapped the genes expressed in the brain cells of people with multiple sclerosis (MS). The atlas, which is presented in the journal Neuron, is hoped to contribute to more personalized treatment of MS in the future.

What does it take to design a new needle for medical use? When the needle needs to be much thinner and sharper than any commercially existing needle and designed to deliver treatments to a previously inaccessible tissue, the answer is years of collaboration between a close-knit team of physicians and engineers.

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects motor neurons. The average life span after diagnosis of this incurable disease is two to five years.

When you are feeling hungry, the brain takes the necessary steps toward consuming a meal. Many of these steps are not well known, but a new study published in the journal Metabolism by researchers at Baylor College of Medicine and the University of Texas Health Science Center at Houston reveals brain circuits and chemical messengers that contribute to the regulation of meal initiation and food intake. The findings have implications for the development of improved therapies to manage obesity, a worldwide epidemic.

Shares in Danish pharmaceutical giant Novo Nordisk, maker of diabetes and weight-loss treatments Ozempic and Wegovy, plunged on Friday after it announced disappointing results of a new drug study.

The World Health Organization and the Rwandan government on Friday declared the outbreak in Rwanda of the Ebola-like Marburg fever over after no new cases were registered in recent weeks.

UAB research has characterized in detail how polymer-based commercial tea bags release millions of nanoplastics and microplastics when infused. The study shows for the first time the capacity of these particles to be absorbed by human intestinal cells, and are thus able to reach the bloodstream and spread throughout the body.