Researchers synthesize chimeric peptide that elicits antitumor activity for cancer immunotherapy

Professor Yanfeng Gao’s team from the School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University have designed and synthesized Pal-DMPOP, a chimeric peptide that can simultaneously block CD47/SIRPα and PD-1/PD-L1. This bispecific peptide elicits synergistic antitumor activity by enhancing macrophages phagocytosis and activating CD8+ T cells. The findings are published in the journal Science China Life Sciences.

‘Oh that happened to me, too!’ Sharing your experiences in conversation is common but sometimes it’s best to just listen

Do you have a friend who responds to almost every anecdote you tell with “Oh my gosh, me too! This reminds me of when that happened to me.” Or perhaps you are that friend. Maybe you instinctively aim to bond with others by talking about experiences you’ve had that feel similar to what your friend has just shared.