Researchers at Nagoya University in Japan have discovered a receptor, sigma-1 receptor, and a protein, ATAD3A, that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease. Since there are drugs that specifically target the receptor, their findings suggest a new therapeutic strategy. They published the study in the journal Neurobiology of Disease.
Map of spinal cord formation gives new knowledge on diseases of the nervous system
Researchers at Karolinska Institutet have mapped how cells in the human spinal cord are formed in the embryo and what genes control the process. Their findings can give rise to new knowledge on how injury to and diseases of the spinal cord arise and how they can be treated. The study has been published in the journal Nature Neuroscience.
Speech rhythm and pitch are fundamental in babies’ language acquisition, shows study
Language acquisition is a complex process that requires different neural and cognitive skills since early childhood. One of children’s big challenges in language learning is to distinguish the words that are grammatically linked to each other, even though they hear one word after the other.
New study questions the efficacy of many osteoarthritis treatments
Recruiting osteoarthritis patients with a lot of pain to clinical studies may give incorrect results if the researcher does not account for the natural variation in pain that occurs with the disease. A research group from Lund University in Sweden is now drawing attention to the traps in clinical studies on osteoarthritis.
Major depressive disorder linked to interplay of gut microbiome and blood metabolome
An international team of medical researchers has found a link between major depressive disorder (MDD) and an interplay between the gut microbiome and the blood metabolome. For their study, reported in the journal JAMA Psychiatry, the group analyzed data in the UK Biobank.
Creating a rat model for testing cell therapies in Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a severe and progressive muscle disorder in which muscle degeneration and necrosis occur due to the absence of a protein called dystrophin. There is no cure for DMD, and as the disease progresses, respiratory and cardiac functions deteriorate, potentially leading to fatal respiratory or heart failure.
Fewer vaccine doses still support pneumococcal immunity, shows clinical trial
A unique study published this month outlines new ways to protect more of the world’s population from vaccine-preventable diseases.
The impact of childhood and teenage anxiety disorders on later life, according to new research
Anxiety rates have been rising in recent years among children and young people, with the situation partially exacerbated by the pandemic.
Oral sex is now the leading risk factor for throat cancer, says researcher
Over the past two decades, there has been a rapid increase in throat cancer in the west, to the extent that some have called it an epidemic. This has been due to a large rise in a specific type of throat cancer called oropharyngeal cancer (the area of the tonsils and back of the throat). The main cause of this cancer is the human papillomavirus (HPV), which are also the main cause of cancer of the cervix. Oropharyngeal cancer has now become more common than cervical cancer in the US and the UK.
Kids and screen time: An expert offers advice for parents and teachers
How much time did your child spend looking at a screen today?