Report: Disease history doubles rate of colorectal cancer screening for family members

To uncover attitudes and the biggest challenges facing colorectal cancer (CRC) awareness and screening, BGI Genomics today released its State of Colorectal Cancer Awareness Report, marking the first-ever global survey report on the world’s third most common cancer. This report is released on World Health Day, April 7, 2023, in line with achieving Health For All, and seeks to motivate action to tackle the health challenges of today and tomorrow.

Novel approach prevents liver damage in animal models of Alagille syndrome

Alagille syndrome, a genetic disease estimated to affect 1 in 30,000 individuals, is caused by mutations in the gene JAG1 in most cases. The mutations affect multiple organs including the liver where it often results in cholestasis, a condition in which the flow of bile from the liver stops or slows, leading to bile buildup that in time causes liver damage. Current treatments focus on delaying disease progression; the only cure for liver disease in Alagille syndrome is liver transplantation.

In bilingual readers, the visual cortex processes Latin and Chinese characters differently

Nearly half of humanity speaks more than one language, and many adults can read and master several writing systems. How does the visual cortex adapt to the recognition of words written with different characters? To answer this question, Laurent Cohen at Paris Brain Institute and the Unicog team led by Stanislas Dehaene at NeuroSpin, CEA’s neuroimaging center, studied the brains of 31 bilingual people.

Using machine learning in the electronic medical record to save lives of hospitalized children

In a report published in Pediatric Critical Care Medicine, a team from Nationwide Children’s Hospital describes a machine learning tool for timely identification of hospitalized children at risk for deterioration—a worsening clinical condition with increased risk of morbidity and mortality. The tool, which is trained on disease-specific groups, promisingly outperformed the existing situational awareness program in identifying at-risk children.