Proteomics is the study and analysis of proteins, including their structures, functions, interactions, and modifications within a biological system. Humans have approximately 20,000 genes that produce over a million different protein variants, including an estimated 100,000 protein isoforms. These protein variants comprise the vast complexity of the proteome that has remained largely unexplored.
How a rogue protein produces ‘Dr. Jekyll and Mr. Hyde’ cancer cells
Melbourne researchers have discovered how a rogue protein produces “Dr. Jekyll and Mr. Hyde” cancer cells, which could lead to improved treatments for melanoma and other cancers.
Imaging brain connections can predict improvements in OCD patients after deep brain stimulation
Deep brain stimulation (DBS) is a promising therapy for treatment-resistant obsessive-compulsive disorder (OCD). A first-of-its-kind collaborative study led by researchers at Texas Children’s Hospital, Baylor College of Medicine, and Brigham & Women’s Hospital has found that mapping neural connections in the brains of OCD patients offers key insights that explain the observed improvements in their clinical outcomes after DBS. The study was published in Biological Psychiatry.
You can find the flow, and scientists can measure it
You know when you’ve found the flow. You experience it when you are doing something that engages you so fully that time seems to fly by. Maybe it’s a job, or something completely different, like chess or computer games or football or shoveling snow.
An advanced pancreatic cancer model for developing personalized therapies
Pancreatic ductal adenocarcinoma (PDAC), is highly aggressive and lethal. It is the most prevalent type of pancreatic cancer, making up 90% of cases; it also has a high rate of metastasis, with an average five-year survival rate of less than 10%.
Personalized gut microbiome analysis for colorectal cancer classification with explainable AI
The gut microbiome comprises a complex population of different bacterial species that are essential to human health. In recent years, scientists across several fields have found that changes in the gut microbiome can be linked to a wide variety of diseases, notably colorectal cancer (CRC). Multiple studies have revealed that a higher abundance of certain bacteria, such as Fusobacterium nucleatum and Parvimonas micra, is typically associated with CRC progression.
Vegan protein supports muscle building as effectively as animal protein, according to study
Fungi-derived mycoprotein is just as effective at supporting muscle building during resistance training as animal protein, according to the findings of a new study from the University of Exeter.
New mouse study reveals a key process in how the brain forms memories
The process by which memories are formed in the hippocampus region of the brain is complex. It relies on a precise choreography of interactions among neurons, neurotransmitters, receptors and enzymes.
Opinion: AI in health care challenges us to define what better, people-centered care looks like
From faster and more accurate disease diagnosis to models of using health care resources more efficiently, AI promises a new frontier of effective and efficient health care. If it’s done right, AI may allow for more people-centered care and for clinicians to spend more time with people, doing the work they enjoy most. But to achieve these aspirations, foundational work must occur in how we operate today and in defining what health care looks like in the future.
Novel lymphoma tumor model paves way for new therapies
In recent years, innovative cancer drugs that target specific molecular drivers of the disease have been embraced as the treatment of choice for many types of cancer. But despite significant advances, there is still a lack of understanding about how the complex interactions between a tumor and its surrounding environment in the body affect cancer progression. This problem has become a well-known roadblock in making novel treatments effective for more people.