Cart is empty Two proteins may be intimately linked to the progression of Parkinson’s disease, a relentless and disabling neurodegenerative disorder that affects millions of people around the world.
Team designs molecule to disrupt SARS-CoV-2 infection
A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.
Pathological mechanism of intellectual disability caused by haploinsufficiency may be a disorder of excitatory synapses
In this study published in Molecular Psychiatry, researchers generated and analyzed Rp58 heterozygous mice as a model of RP58/ZBTB18 haploinsufficiency and were able to clarify the following four points.
Leprosy, scabies and yaws: Togo’s neglected tropical skin diseases need attention, says study
Neglected tropical diseases are a group of 20 diseases found mostly in tropical regions that are strongly associated with poverty. Among them are skin diseases like scabies, leprosy and yaws. They are caused by some bacteria, viruses, mosquitoes or mites and, according to the World Health Organization (WHO), they affect more than one billion people worldwide, mainly in lower-income settings.
What causes hiccups and how can you get rid of them?
We all get hiccups from time to time, and sometimes they just won’t seem to go away.
Researchers discover two subtypes of insulin-producing cells
A team led by Van Andel Institute and Max Planck Institute of Immunobiology and Epigenetics scientists has identified two distinct subtypes of insulin-producing beta cells, or ß cells, each with crucial characteristics that may be leveraged to better understand and treat type 1 and type 2 diabetes.
Researchers propose a novel biomarker for early diagnosis of Alzheimer’s disease
Alzheimer’s disease is the most prominent cause of dementia affecting millions of people worldwide. As the changes in the brain function starts 10–20 years before the clinical onset of Alzheimer’s disease, there is a strong interest in the identification of early markers that can be predictive of future mental health/cognitive decline. This is something that we researchers at the Karolinska Institute are on the lookout for. Our latest study is now published in Nature Reviews Neurology.
Time-restricted eating vs. daily calorie restriction in reducing nonalcoholic fatty liver disease
Adults with obesity and nonalcoholic fatty liver disease did not see additional reductions in intrahepatic triglyceride while on a time-restricted eating regimen compared to subjects on a daily calorie-restriction diet. This is according to a recent study published in the journal JAMA Network Open and led by researchers at Southern Medical University in Guangzhou, China and colleagues in the US at Tulane University School of Public Health and Tropical Medicine in New Orleans.
PPP remains the best model for infrastructure development – Milupi
By NATION REPORTER
GOVERNMENT does not care whether the National Pensions Scheme Authority (NAPSA) proceeds to enter a deal with Macro Ocean or not because they have a choice to do so or not without any interference from anywhere, Infrastructure Minister Charles Milupi has said.
Mr Milupi said Government was only concerned with the concessioner reaching a financial clause regardless of where they will get the money so that the construction of the Lusaka-Ndola dual carriage way could take off.
He said nobody in the government has directed NAPSA to work with Micro Ocean Investment Consortium and vice versa and that the two were free to agree without involving the government.
“You cannot get into a deal with the concessioner and at the same time direct them that you should go and get your money from that particular institution, that is not the way PPP works. There is no scam whatsoever in this arrangement,” Mr Milupi said.
Mr Milupi said the responsibility of actualising the deal remained with the concessioner to come up with a full package to sponsor the entire project whether local financial lending institutions participate or not.
He said after the deal is entered with the concessionaire the Public Private Partnership (PPP) act would mandate the concessioner to reach financial clauses for which within a period of time of six months, the financiers could be their own shareholders or lenders from outside the country or within.
Mr Milupi said the opposition were not happy with what the UPND had achieved and that they were using all forms of propaganda to make the government fail at every stage.
He said the UPND inherited a collapsed economy and a huge burden of debt such that the government could not borrow anymore in order to undertake infrastructure development projects thus embarking on PPP models that did not stress the treasury.
Research calls for more consumer protection to combat double danger of gambling with cryptocurrencies
A new study has highlighted how cryptocurrency investors often suffer gambling-related harms—and online gambling outlets accepting cryptocurrency as wagers pose even greater risks.