Scientists create dental equipment that destroys viruses

Three years of the COVID-19 pandemic particularly affected the daily life of health care professionals, who consulted patients remotely due to being more likely to get infected, and some of them, like dentists, were even prohibited from working. A new invention by Lithuanian scientists can allow for providing health care services and ensure the safety of specialists during the outbreaks of various diseases.

Study: Mea6 deficiency in oligodendrocytes affects white matter formation in the brain

About half of adult human brain volume is made up of white matter. Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons to form the major components of white matter. Abnormal myelin sheath is associated with many neurological diseases. Mea6/ cTAGE5C is essential for vesicle trafficking from ER to Golgi. However, its biological function in oligodendrocyte and white matter development remains unclear.

In vitro 3D-engineered heart tissue that monitors drug-induced cardiotoxicity

Cardiotoxicity is a clinical condition that arises from using pharmaceutical agents such as antibiotics, which result in harmful effects on the heart, ultimately compromising its functional capacity. The left ventricle’s contractile ability is impaired, potentially leading to heart failure, a severe clinical outcome. Recently, a joint team of researchers from POSTECH and Georgia Institute of Technology successfully created an engineered heart via 3D printing technology that allows for early monitoring of drug-induced cardiotoxicity.

Researchers discover two-pronged approach to stimulate STING antitumor activity

Immunotherapies have greatly improved the outcomes of many patients with melanoma. But there is still a need for new approaches for the subset of patients who do not respond well to this type of therapy. Moffitt Cancer Center researchers are looking at new targets to help inhibit tumor development and promote antitumor immunity, one being the STING signaling pathway. In a new article published in Nature Communications, a team of Moffitt and University of Miami Miller School of Medicine investigators demonstrate that targeting the STING pathway with a combination strategy results in improved antitumor activity.