Perivascular cells could induce microglial malfunction associated with Alzheimer’s disease

Microglia, the primary immune cells in the central nervous system, defend humans and animals from infections by “eating” pathogens, dead cells, toxic proteins and other debris in the brain. Recent neuroscience studies have consistently highlighted the role of microglia in the development of Alzheimer’s disease (AD) and other neurodegenerative diseases, suggesting that they can sometimes start “eating” or engulfing crucial connections between neurons.

Study: Post-bariatric surgery exercise modulates brain regions associated with regulation of food intake

Physical exercise practiced by patients submitted to bariatric surgery acts on brain regions involved in food intake, reducing hunger or accelerating satiety, for example. This was the result observed in a clinical trial conducted at Hospital das Clínicas (HC), the hospital complex run by the University of São Paulo’s Medical School (FM-USP) in Brazil. An article on the study, pointing to positive effects of exercise on obesity-related conditions in post-bariatric patients, is published in the International Journal of Obesity.

Transcriptomic changes in glia linked to specific neurodegenerative diseases

Neurodegenerative disorders such as Alzheimer, Parkinson and Huntington disease each cause their own distinct set of symptoms, yet they share a common feature: abnormal protein aggregation. It’s been unknown if overlapping cellular pathways underly the damaging accumulation of proteins in these diseases. Mounting evidence demonstrates how glial cells such as astrocytes and microglia play a key part in neurodegenerative disease.

New AI model using social media posts may help predict community deaths from opioid use

Clinicians and other professionals trying to stop the opioid crisis in the United States need all the tools they can to accurately identify communities at risk of large increases in deaths from opioid use and prevent deaths. A study led by a team of computer scientists at Stony Brook University and published in npj Digital Medicine presents a unique approach using artificial intelligence (AI) and social media posts to predict opioid mortality rates.

Dedicated protocol of hyperbaric oxygen therapy found to be more effective for fibromyalgia caused by head injury

Researchers from Tel Aviv University compared treatment with a dedicated protocol of hyperbaric oxygen therapy (HBOT) to the pharmacology (drugs) treatment available today for patients suffering from fibromyalgia as a result of a traumatic brain injury (TBI). The researchers found that the dedicated hyperbaric oxygen therapy is much more effective in reducing pain than the drug treatment, and it even resulted in the healing of 2 out of 5 patients.

‘You are not alone’: Q&A with expert on sleep, stress and memory in women

Women often talk about the struggles they face feeling pinched between family and work obligations. As a result, many have trouble getting enough quality sleep, managing stress and maintaining a healthy work-life balance. These issues are very near and dear to the heart of Notre Dame’s Jessica Payne, professor of psychology and director of the Sleep, Stress and Memory (SAM) Lab, whose research focuses on how sleep and stress influence psychological function, well-being and human memory.