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More than 30 million Americans—roughly 12 percent of the U.S. population—rely on prescription opioids. A new Western University-led study reveals high use among particular groups, including women and those who are food-insecure; findings the researchers hope will aid policymakers and practitioners in addressing this important issue.

For young people, empagliflozin is associated with improvement in glycated hemoglobin (HbA1c), according to a study published in the March issue of The Lancet Diabetes & Endocrinology.

A new research paper titled “Age-related methylation changes in the human sperm epigenome” has been published in Aging.

For many people who have heart failure, supervised exercise training is safe and may offer substantial improvement in exercise capacity and quality of life, even more than medications, according to a new, joint scientific statement from the American Heart Association and the American College of Cardiology. The statement is published today in both the journal Circulation and in the Journal of the American College of Cardiology.

New research from the University of Hertfordshire has found that a mobile-phone game app can help identify ongoing problems with navigation—a common long-term symptom of traumatic brain injuries (TBIs)—making these issues easier to diagnose and treat.

The cellular glitches underlying a rare genetic disorder called activated PI3K Delta syndrome 2 (APDS2) have been identified by researchers at the Garvan Institute of Medical Research. The disorder is caused by genetic variations that disrupt immune cell signaling through a protein called PI3K.

The implementation of minimum unit pricing (MUP) legislation is associated with significant reductions in alcohol-specific deaths among those from the most socio-economically deprived areas in Scotland, suggests a new study published in The Lancet.

There’s little evidence to suggest that children conceived as a result of fertility treatment are at any greater risk of pregnancy complications or worse birth outcomes than their naturally conceived peers, finds a long term study, published in the open access journal BMJ Medicine.

In 2012, Michael Cruz exercised a lot. Four years into a 15-year prison sentence, this was one of the only things he had, he says, until he noticed a numb, tingling sensation in one of his toes while working out. At first, he dismissed the feeling. But it persisted, and over time, spread up his ankle. Then, he began experiencing little sharp pains in his back, which he attributed to muscle spasms from his workouts. Months later, the tingling sensation had encompassed his body up to his belly button. And when he woke up one morning, legs shaking and unable to walk, he knew he needed to see a doctor.

An LSU Health New Orleans study demonstrated the effectiveness of single, focused Interprofessional Education (IPE)-based exercises in preparing young health professions learners to limit or prevent alcohol use disorder (AUD). Students learned together as a foreshadowing of future interprofessional practice. This intervention produced significant decreases in the stigma associated with alcohol use, which is highly relevant for potential AUD patients. Results are published in BMC Medical Education.