Cart is empty Weill Cornell Medicine investigators have developed a technique to help surgeons reconstruct more natural-looking nipples for patients who have undergone breast reconstruction after mastectomy to treat breast cancer.
Study: Mitochondria engage the integrated stress response to promote tumor growth
A new editorial paper, titled “Mitochondria engage the integrated stress response to promote tumor growth,” was published in Oncotarget.
Study: Higher fracture risk after total hip replacement when cementless implant used to treat femoral neck fracture
A study by Hospital for Special Surgery (HSS) and other centers found that total hip replacement performed with a cementless prosthesis for a femoral neck fracture led to a higher rate of a second fracture and subsequent revision surgery. The research was presented today at the American Academy of Orthopaedic Surgeons (AAOS) Annual Meeting in Las Vegas. The results were also published online in The Journal of Arthroplasty in October 2022.
BMI affects long-term outcomes of ‘partial’ knee arthroplasty
For patients with higher body mass index (BMI) undergoing unicompartmental or “partial” knee replacement (UKR), long-term outcomes are improved when the implant is placed using a cementless rather than cemented technique, reports a study in the Journal of Bone and Joint Surgery.
Digital rectal examination is not useful to early detect prostate cancers, says new research
A common method of detecting prostate cancer may not be accurate enough as a reliable screening tool by itself, scientists have warned.
New approach to improving clinical trial enrollment and diversity
Before new therapies can reach patients, they must be tested in clinical trials in representative populations to show that they work and are safe. Failure to enroll enough participants in trials can delay the arrival of new therapies in the clinic and inflate their eventual price tags. Failure to recruit diverse patients could diminish the relevance and generalizability of trial findings. For example, a drug that proves effective for White patients might not work as well in people of other races or ethnicities.
Long COVID is much less likely after omicron than after initial pandemic variant, finds new research
The omicron variant of SARS-CoV-2 is much less likely to lead to long COVID than the variant circulating at the start of the COVID-19 pandemic, new research being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023, Copenhagen, April 15-18) suggests.
AI-powered ultrasound imaging that detects breast cancer
Breast cancer undisputedly has the highest incidence rate in female patients. Moreover, out of the six major cancers, it is the only one that has shown an increasing trend over the past 20 years.
Characterization and determinant factors of critical illness and in-hospital mortality of COVID-19 patients in Kenya
Globally, there is an anticipated epidemiological heterogeneity of COVID-19 patients. No epidemiological studies validated the epidemiological characterization of COVID-19 patients in African settings.
Scientists develop new targeted therapeutic strategies to fight liver metastasis
The research group led by Prof. Zeng Zhutian from the Division of Life Sciences and Medicine of the University of Science and Technology of China (USTC) revealed a new mechanism of immune surveillance by liver-resident macrophages called Kupffer cells (KCs) that prevent liver metastasis from occurring. They also developed a new method for in situ targeted expression and remodeling of KCs’ anti-tumor function, which successfully cleared tumors in various animal models with end-stage liver metastasis, thus providing a new approach to developing clinical immunotherapy for metastatic liver cancers.