Posts in category: Uncategorized

Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease that can affect multiple tissues and organs. Common manifestations of SLE include fever, fatigue, malar rash, oral ulcer, alopecia, arthritis, and nephritis. Women of childbearing age are most likely to suffer from SLE. Currently, there is no cure for SLE, and it lacks an effective and safe treatment regimen because its underlying etiopathogenesis remains elusive.

New findings from researchers at Wake Forest University School of Medicine confirm that the rates of Type 1 and Type 2 diabetes continue to increase in children and young adults. Non-Hispanic Black and Hispanic children and young adults also had higher incidence rates of diabetes.

Recent studies have provided strong evidence that patients with heart failure can benefit from medical therapies that can reduce risk of worsening symptoms and extend patients’ lives. But despite new guidelines, adoption of these therapies has been slow, incomplete and inequitable.

In the first nationally representative survey of U.S. adults on reasons for trust in federal, state, and local public health agencies’ information during the COVID-19 pandemic, researchers at Harvard T.H. Chan School of Public Health and colleagues found that the Centers for Disease Control and Prevention (CDC) was highly trusted for information by more than one-third of U.S. adults, whereas state and local health departments were highly trusted by about one-quarter. An additional 37-51% of adults trusted these public health agencies somewhat, and less than 10% reported no trust at all in these agencies for health information.

A study led by researchers from IGTP’s Immunology of Diabetes group has identified new microRNA as biomarkers for the partial remission phase, also known as “honeymoon phase,” of type 1 diabetes, and has linked the miR-30d-5p microRNA to immunoregulatory processes that may take place during this phase.

Robots in medical care and rehabilitation are becoming increasingly prevalent. They promise to meet patients’ needs by personalizing physical and social interactions with users. However, tailoring robots to users is about more than just making the robot adjustable or personalized to the users’ tastes. It is also about ensuring design justice (i.e., a design theory that rethinks design processes, places marginalized groups at the center of the design process, and exploits collaborative, creative practices to overcome exclusion challenges) and understanding how inclusive robot design is to interact with the user in a natural, non-discriminatory way.

Weaknesses in the United States laboratory system, which were illuminated during the COVID-19 pandemic, underscore a need for policy changes to improve the country’s infectious disease response, according to a new analysis by a Weill Cornell Medicine investigator.

For people with alcohol use disorder (AUD), there is a constant, vicious cycle between changes to the brain and changes to behavior. AUD can alter signaling pathways in the brain; in turn, those changes can exacerbate drinking.

When it comes to chronic infections and cancer, a particular type of immune cell plays a central role in our defenses. Researchers at the University of Basel have uncovered the key to the tenacity of these immune cells in coping with the marathon that is fighting a chronic infection. Their results lay the foundations for more effective therapies and vaccination strategies.

Millions of people around the world undergo some type of orthodontic treatment each year due largely to developmental deformities in the jaw, skull, or face. Computed tomography (CT) imaging is the go-to technique for surgeons when planning such treatments, especially surgeries. This is because CT provides 3D images of the bones and teeth, which helps the surgeon analyze complex cases in detail and determine the best treatment procedure based on that.