New research from Boston Medical Center and Boston University School of Public Health found that municipalities with high numbers of opioid-related emergencies that introduced post-overdose programs were associated with lower opioid related death rates over time when compared to those that did not implement these programs. Published in JAMA Psychiatry, the study showed that implementation of these outreach programs was also associated with a significant and gradual reduction of opioid emergency response rates.
Participation in program for patients hospitalized with COVID-19 increases likelihood of home discharge
The Acute Hospital Rehabilitation Intensive Service (ARISE) program, developed in 2020 by the Johns Hopkins Department of Physical Medicine and Rehabilitation (PM&R), may increase the chances of patients hospitalized with COVID-19 getting discharged to their home rather than to a rehabilitation facility that provides post-hospitalization care services.
Study: Social risk screening and referral addresses the high burden of unmet needs among NICU families
Poverty and adverse social determinants of health, namely unmet social needs, have well established detrimental effects on the health and development of children and the health and well-being of their caregivers. While social risk screening is recommended by the American Academy of Pediatrics, this practice is underutilized in neonatal intensive care units (NICU). The prolonged NICU hospitalization offers a unique opportunity to identify and address unmet social needs among low-income families of hospitalized newborns.
Small changes in children’s sleep lead to significant changes in eating habits, shows study
Just an hour less sleep a night affects what and how children eat, University of Otago research shows.
Comparison with Canada highlights poor access to US methadone treatment
People living in the United States must travel significantly farther to access methadone treatment for opioid addiction than Canadians, suggests a new study led by Washington State University researchers.
Pain in the back: Preventing and treating spinal arthritis
Many types of arthritis can affect your musculoskeletal system. Joints are physical points of connection between two bones, and cartilage is the tissue that covers the surface of the bone at the joint. A membrane, called the synovial membrane, lines the joint and is filled with fluid known as synovial fluid. All these components work together to make movement easy.
Artificial sweetener found to dampen immune response to disease in mice
Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.
Scientists discover key information about the function of mitochondria in cancer cells
Scientists have long known that mitochondria play a crucial role in the metabolism and energy production of cancer cells. However, until now, little was known about the relationship between the structural organization of mitochondrial networks and their functional bioenergetic activity at the level of whole tumors.
Study unravels a cause of resistance to novel drug in patients with acute leukemia
A new targeted drug has not only sparked remissions in patients with a common form of leukemia but also induced the cancer cells to reveal one of their schemes for resisting the drug, investigators at Dana-Farber Cancer Institute and other research centers report in a new pair of studies in the journal Nature.
Targeting menin induces responses in acute leukemias with KMT2A rearrangements or NPM1 mutations
Researchers from The University of Texas MD Anderson Cancer Center showed that inhibiting menin with revumenib, previously known as SNDX-5613, yielded encouraging responses for advanced acute leukemias with KMT2A rearrangements or mutant NPM1. Findings from the Phase I AUGMENT-101 trial were published today in Nature.