Posts in category: Uncategorized

Scientists at Open Targets, EMBL’s European Bioinformatics Institute (EMBL-EBI), and GSK are revealing the shared basis of diseases using a map of interacting human proteins. By helping to understand how biological processes affect human traits and diseases, this work will prioritize new targets for drug discovery and identify drug repurposing opportunities.

Despite widespread agreement that clinical trials should enroll a representative sampling of individuals from different age, gender, and racial and ethnic groups, a new Yale School of Medicine study shows that clinical trials on new cancer drugs still fall far short of including key data on several demographic groups. The findings were published in the journal BMJ Medicine.

A new study by CUNY SPH doctoral student Thinh Vu and colleagues reveals that cancer inpatients experience high levels of symptoms related to depression and anxiety, as well as significant impairment in mobility and daily activities.

Dementia has overtaken coronary heart disease as the leading cause of disease burden among Australians aged 65 and over.

Infection with SARS-CoV-2 leads to severe disease in some people, while others do not get ill or only experience mild symptoms. But why is this the case? Unfortunately, we do not know exactly. We do know that an overactive innate immune system is causing severe COVID-19 disease, but it is unclear how this is regulated.

Insulin is not only a regulator of blood sugar, but also has an influence on life expectancy. If the insulin signaling pathway is inhibited, animals live longer. But which tissue is crucial for this? And do males and females react in the same way?

Medication abortions in the United States usually involve two different drugs.

South African health authorities on Thursday announced the country’s first cholera death in more than a decade.

Men who never married were more than twice as likely to die within about five years after a heart failure diagnosis compared with women of any marital status or men who were previously married, according to a study presented at the American College of Cardiology’s Annual Scientific Session Together With the World Congress of Cardiology.

To eat or to mate—that is the question (and the answer is: moderately hungry mice choose to mate). Researchers publishing in the journal Cell Metabolism on Thursday, February 23, show that hungry mice prioritize interacting with members of the opposite sex over eating and drinking when their brains are stimulated with leptin, an appetite-suppressing hormone.