Posts in category: Uncategorized

The growing number of Alzheimer’s disease (AD) cases, projected to reach 135 million by 2050, highlights the urgent need for effective therapeutics. Accumulated evidence points to an impairment of the metabolic mechanism in Alzheimer’s patients that develops several decades before the onset of dementia and deterioration of cognitive function. Reduced metabolism results from a dysfunction of the mitochondria, which is responsible for producing most of the energy in the cell but is also involved in cell death, inflammation and immune response.

A research team led by Dr. Tu Yiheng from the Institute of Psychology of the Chinese Academy of Sciences has found that people with chronic pain in multiple parts of the body had a higher risk of dementia and experienced broader and faster cognitive decline, including memory, executive function, learning, and attention.

In a new study, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) link obesity with 21 Alzheimer’s disease-related genes, providing a potential mechanistic explanation for why Alzheimer’s is sometimes more frequent among adults who experienced obesity in midlife.

According to trends in male reproductive health data, sperm quality and testosterone levels have declined over the last few decades, sounding alarm bells for Michael Eisenberg, MD, a professor of urology at Stanford Medicine. It’s made him wonder: Should we be concerned about other differences in men’s reproductive health? Surmising that there may be more to uncover, Eisenberg set out to determine if physical anatomy has changed.

In a new study from Tel Aviv University published in the journal Nature Cancer, a team of researchers led by Prof. Neta Erez, head of the laboratory for the biology of tumors from the Department of Pathology at the Sackler Faculty of Medicine, identified and characterized a new mechanism that facilitates the formation of brain metastases and found that impairing this mechanism significantly reduced the development of brain metastases in mice.

 TWO workers at a farm in Lufwanyama have betrayed the trust of their master, stealing his livestock and supplying their Chinese buyer. Yona Kakingila, a farm caretaker and his casual worker friend Chilekwa Munkonge are accused of stealing a goat and two sheep valued at K4500 from their boss Dickson Ikuma. Police said the stock […]

Mount Sinai researchers have published a study in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association that sheds new light on the role of DNA methylation in Alzheimer’s disease (AD). The study found that DNA methylation has a profound impact on gene and protein co-expression networks associated with AD and could lead to the discovery of new neuropathological processes and molecular mechanisms for developing novel treatments for the disease.

By MILLENNIUM REPORTER
PATRIOTIC Front (PF) Presidential hopeful Greyford Monde says, there is need to realign policies in the country in order to uplift the welfare of the youths in the country.
Speaking when he featured on Millennium TV programme dubbed “The common room, Mr Monde said, nothing much has been done to support the youth which has resulted in them languishing in poverty.
Mr Monde said, despite the new dawn administration promising jobs and empowerment to the youths, it has failed to fulfill the promise.

Frequent pins and needles may be a sign of an underlying condition such as nerve damage, diabetes, and alcohol abuse, Fred Pescatore, a family physician based in New York City, said.

A NATIONAL Registration Passport and Citizenship, assistant registration officer, has told the Lusaka Magistrate court that it was wrong for Lusaka business executive, Harry Findlay to hold more than one passport.
Mr. Mulenga Kaliwile said this was because Findlay had reported to the office that his passport was lost when he went to obtain a new passport.
He told Lusaka Principal Magistrate Sylvia Munyinya during cross examination yesterday that Findlay obtained another passport because the one he had got was lost and he needed another one. Findlay is charged with two counts of holding more than one passport and found with endorsements of forged immigration stamps.
It is alleged that Findlay on March 14 2017, at Lusaka did acquire a Zambian ZPO21382 passport number purporting to have lost a Zambian passport number ZPO13259 when in fact not.
In the second counts, Findlay is alleged to have being found with a forged immigration endorsements of forged immigration stamp in a passport found in possession of endorsements of forged immigration stamps for Mwami Immigration Border Control in his passport number ZPO32178 purporting to show that it was officially endorsed when in fact not. But during cross examination led by one of the defence lawyers, Milner Katolo, when asked if there was anything wrong with Findaly holding more than one passport, Mr Kaliwile said there was wrong because when he obtained Zambian ZPO21382 he had lost his Zambian passport number ZPO13259.
He insisted when asked by Mr Katolo what was wrong with Findlay having passports which were regularly issued to him by the passport office that there was something wrong because the records indicated that his earlier passport no .ZPO13259 got lost.
Mr Kaliwile explained that once a passport was reported missing and replaced it was not supposed to continue being used.
Further, in cross examination by another defence lawyer, Charles Changano, Mr Kaliwile agreed that a passport was only issued to a person when they met the requirements and the passport office was satisfied.
He said that upon being issued with the passport, both the passport officer and passport holder were supposed to sign to confirm that everything was in order.
He further explained that he never signed any of Findlay’s passports but were signed by a Mr Nkhoma who was now deceased. He agreed in continued cross examination by defence lawyer Jonas Zimba that he did not tell the immigration that previous passports which were issued to Findlay were not cancelled. Trial continues on March 3, 2023