A research group has made significant progress in investigating the therapeutic effects and molecular mechanisms of stilbene-enriched extracts from the leaves of Cajanus cajan (L.) Millsp.(C. cajan) as a potential therapeutic agent for psoriasis.
Pet dogs linked to antimicrobial-resistant Salmonella spread
Antibiotic-resistant Salmonella is a serious public health concern that has increased in recent years as the bacteria have developed ways to survive drugs. According to the U.S. Centers for Disease Control and Prevention, people can get Salmonella from eating contaminated food products or from infected people or animals—typically via unintentional contact with feces via touching hands or stroking a pet.
GLP-1 Zepbound is approved as first drug for sleep apnea
The U.S. Food and Drug Administration (FDA) has approved the first prescription medication specifically for treating obstructive sleep apnea (OSA): the weight-loss drug Zepbound.
Disparities seen in biennial mammography screening for women in their 40s
For women aged 40 to 49 years, there are considerable disparities and gaps in biennial mammography screening, according to a research letter published online Dec. 20 in JAMA Network Open.
Upadacitinib found to improve ulcerative colitis outcomes at 12 months
For patients with ulcerative colitis, upadacitinib is associated with improved disease-specific outcomes at 12 months compared with tofacitinib, according to a study published in the December issue of the American Journal of Gastroenterology.
Parents, clinicians skeptical of children’s high blood pressure readings
Both parents of children with hypertension and treating clinicians are aware of the importance of addressing pediatric hypertension but show significant mistrust in clinic blood pressure measurements, according to a study published online Dec. 13 in JAMA Network Open.
What can fecal proteins reveal about heart health?
Human and microbial proteins found in feces could help doctors detect a long-term risk of deadly cardiovascular conditions in otherwise healthy patients, avoiding the need for costly and invasive diagnostic procedures.
HIV stigma can now be more dangerous than the virus—research shows how to address this
Speaking at the 16th International Aids Conference in 2006, the then UNAids executive director, Peter Piot, remarked: “Since the beginning of the epidemic, stigma, discrimination and gender inequality have been identified as major causes of personal suffering, and as major obstacles to effective responses to HIV.”
Gene editing tool reduces Alzheimer’s plaque precursor in mice
A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer’s disease, researchers at the University of Illinois Urbana-Champaign report.
Lithium shows promise in treating autism-related symptoms in mouse study
A discovery has highlighted lithium—a drug long used to treat bipolar disorder and depression—as a potential therapy for autism spectrum disorder (ASD). This research, conducted by a team at the Center for Synaptic Brain Dysfunctions within the Institute for Basic Science (IBS) led by Director Kim Eunjoon, reveals that lithium can restore brain function and alleviate behavioral symptoms in animal models of ASD caused by mutations in the Dyrk1a gene.