Low-dose apixaban comparable to full dose for preventing venous thromboembolism recurrence in patients with cancer

Patients with active cancer who developed a blood clot, or venous thromboembolism (VTE), and were treated with blood-thinning medication for at least six months, followed by an additional 12 months of low-dose apixaban, experienced similar VTE recurrences and less bleeding as similar patients who received a full dose of the oral blood-thinning medication over the same extended period. These findings from the API-CAT trial were presented at the American College of Cardiology’s Annual Scientific Session (ACC.25).

Virtual reality-based system shows potential for improving psychiatric diagnoses

Researchers have developed a virtual reality-based system that shows promise in improving the differentiation between common mental health conditions, potentially paving the way for earlier and more personalized treatment. The work is published in the March edition of the journal European Neuropsychopharmacology, with a subsequent comment also being published in the same journal.

Prothrombin concentrate superior to frozen plasma in controlling bleeding during heart surgery

In patients experiencing excessive bleeding during cardiac surgery, a concentrated blood product containing proteins that help the blood clot was significantly more effective and caused fewer adverse effects than frozen plasma, the standard therapy, according to a study presented at the American College of Cardiology’s Annual Scientific Session (ACC.25). The concentrated product, known as four-factor prothrombin complex concentrate (4F-PCC), reduced patients’ risk of experiencing a major bleeding event by close to half compared with standard treatment.