Long COVID can result in increased risk for a variety of serious health problems for young people, including those affecting the kidney, gut, and cardiovascular system, according to a group of new studies led by investigators at the Perelman School of Medicine at the University of Pennsylvania.
Basal cell carcinoma’s low immunogenicity linked to suppression of antigen presentation from its cell of origin
Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune-based therapies). Despite harboring the highest tumor mutational burden of all cancers, basal cell carcinomas (BCCs) have low immunogenicity.
Montana has a measles outbreak with its first cases in 35 years. Here’s what you should know
Montana is the ninth U.S. state to have an active measles outbreak.
Single-dose psychedelic boosts brain flexibility for weeks, study finds
University of Michigan researchers have discovered that a single dose of a psychedelic compound can enhance cognitive flexibility—the brain’s ability to adapt to changing circumstances—for weeks after administration, potentially revolutionizing treatments for depression, PTSD, and neurodegenerative diseases.
Sex differences may drive substance use patterns in panic disorder patients
In a research article, researchers have revealed compelling evidence that biological sex significantly influences substance use patterns among individuals with panic disorder, with implications for both clinical assessment and treatment strategies.
Medication-induced sterol disruption: A silent threat to brain development and public health
An editorial published in Brain Medicine raises the alarm about a previously overlooked threat to brain development and public health: the disruption of sterol biosynthesis by common prescription medications.
Middle-aged Americans report higher loneliness than older adults, global study finds
Middle-aged Americans have demonstrated some of the highest levels of loneliness in a new study assessing tens of thousands of 50-to-90-year-olds across 29 countries.
Combining brain stimulation with speech therapy shows promise for restoring language in primary progressive aphasia
Primary progressive aphasia is a neurological condition that causes a gradual decline in language abilities. There is no cure or medication that can reverse or stop the progression of PPA. The standard practice in the clinical setting is speech-language therapy to help people with PPA maintain their ability to communicate.
Using pilocarpine drops post goniotomy may reduce long-term glaucoma medication needs
Using pilocarpine eye drops following Kahook Dual Blade (KDB) goniotomy surgery may improve clinical outcomes for patients with glaucoma and reduce the need for future medications, according to new research published by faculty members and trainees in the Department of Ophthalmology at the University of Colorado School of Medicine. The study is published in the journal Current Eye Research.
Psilocybin use rises across all age groups following 2019 decriminalization
A multisource observational study aimed to quantify the change in prevalence and health care utilization of psilocybin users between 2014 and 2023. The study found that the prevalence of psilocybin use increased across all age groups, with those with mental or physical comorbidities among the most common users.