Parkinson’s disease (PD) and Lewy body dementia (LBD) are incurable and progressive neurodegenerative disorders, with some overlapping symptoms. An estimated 10 million people worldwide live with PD, while the figure for LBD—the second most common form of dementia after Alzheimer’s—is unclear. Both diseases involve Lewy bodies—abnormal clumps of α-synuclein protein in brain cells.
First participant with Down syndrome joins Alzheimer’s prevention trial
Researchers have dosed the first participant in a clinical trial of an investigational medicine designed to lower the amount of amyloid precursor protein (APP) for the potential treatment of Alzheimer’s disease (AD), which is initially being studied in adults with Down syndrome (DS) who have a genetic risk of developing AD.
Extraordinary outcomes for robot-assisted, minimally invasive esophagectomy
Roswell Park Comprehensive Cancer Center achieved textbook outcomes for 90% of 150 consecutive robot-assisted, minimally invasive esophagectomies (RAMIE) performed from 2020–2024, as reported in a study published in the Journal of Gastrointestinal Surgery.
Invasive water hyacinth harnessed for women’s hygiene
In a casual conversation, researcher Pooja Singh and two of her colleagues were discussing the idea of developing biodegradable sanitary pads and started to contemplate what raw materials to use.
Most COVID-19 treatments found to be free of serious side effects in analysis of US studies
Numerous treatment options for COVID-19 have been approved by the U.S. Food and Drug Administration over the last four years, including antiviral drugs and monoclonal antibodies that suppress an excessive immune response. Now, research from the Keck School of Medicine of USC has found that COVID-19 therapies cause few serious side effects, based on an evaluation of the full spectrum of evidence available from U.S. biomedical science.
Better cleaning of hospital equipment could cut patient infections by one-third—and save money
Hospital-acquired infections are infections patients didn’t have when they were admitted to hospital. The most common include wound infections after surgery, urinary tract infections and pneumonia.
Lab-grown meat: You may find it icky, but it could drive forward medical research
Lab-grown meat causes heated debates. Proponents see benefits for the climate and animal welfare. Opponents worry about a Frankenstein food they regard as risky and unnatural. Whatever your opinion, the technology underpinning cultivated meat is moving fast to create large pieces of muscle tissue.
Eviction bans linked to drop in child abuse reports
Eviction bans implemented during the COVID-19 pandemic had an unexpected positive benefit for America’s children, a new study says.
UK approves ‘landmark’ breast cancer drug
A new drug that helps slow the spread of an incurable type of breast cancer has been approved for use in Britain’s state-run National Health Service, officials said on Friday.
New AI chatbot for parents improves HPV vaccine uptake
The first trial of an AI-powered chatbot designed to inform parents about the HPV vaccine has shown that it increases vaccine uptake and engagement with health professionals.