Natural compounds derived from soy and other plants found to reduce breast cancer recurrence and improve survival

Soy compounds called isoflavones are among the plant-derived compounds that may significantly reduce the risk of breast cancer recurrence or death, according to a new meta-analysis co-directed by investigators from the Johns Hopkins Kimmel Cancer Center. The results were published Jan. 10 in the journal JNCI Cancer Spectrum.

Study draws lessons about drug policy by examining history of fireworks regulation, prohibitions

Policymakers worldwide wrestle with whether to prohibit products that can harm consumers. Prohibitions can reduce consumption and consumption-related harms, but also create other problems, including illegal markets. In a new study, researchers have reviewed the history of fireworks regulations, sales, and harms, then contrasted these with those for cannabis. They found a surprising number of similarities as well as some key differences between the two.

Research finds dark web fentanyl-selling operations have grown rapidly, offer steep discounts

Overdose deaths in North America have skyrocketed, primarily because of the spread of illegally manufactured fentanyl. In a new study, researchers have analyzed an early and prominent fentanyl-selling operation on the dark web. The organization sustained a significant growth rate, which allowed it to offer consumers steep discounts. In light of these findings, the authors conclude that it might be challenging to constrain supply by shuttering individual organizations since remaining organizations could grow rapidly to fill unmet demand.

Study: High-school students with neurodevelopmental disorders experience worse premenstrual syndrome symptoms

Premenstrual syndrome (PMS) is a relatively common condition that affects most women who menstruate, at some point in their lives. Typically, PMS can cause a variety of symptoms, including mood swings, irritability, bloating, and fatigue. Moreover, PMS tends to worsen the symptoms of certain psychiatric and personality disorders. In certain instances, PMS can lead to premenstrual dysphoric disorder (PMDD), a type of severe depressive disorder that impairs daily life activities and interpersonal relationships.