In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.
New research indicates that the eating disorder anorexia nervosa is associated with being an early riser, unlike many other disorders that tend to be evening-based such as depression, binge eating disorder and schizophrenia.
A detailed ‘atlas’ of neuroblastoma tumors points to a new target for immunotherapy. Scientists from the Princess Máxima Center for pediatric oncology in the Netherlands mapped this childhood tumor at the level of individual cancer and immune cells. In doing so, they discovered a brake on the immune system that can be blocked with existing immunotherapy. The results in the lab are promising; preparations for a clinical study are underway.
A trio of pediatricians at Cohen Children’s Medical Center, in New York, has found ChatGPT’s pediatric diagnostic skills to be considerably lacking after asking the LLM to diagnose 100 random case studies. In their study, reported in the journal JAMA Pediatrics, Joseph Barile, Alex Margolis and Grace Cason tested ChatGPT’s diagnostic skills.
Age-related macular degeneration is a common disease of aging and a leading cause of blindness in older adults, although blindness can be prevented if AMD is treated early. Advanced AMD is treatable only in about 15% of cases by injecting medications directly into the eye, which is burdensome and expensive for patients and their families.
A team of medical researchers at Washington University School of Medicine, working with colleagues from the University of Zambia School of Medicine and Cedars-Sinai Medical Center, has developed a regimen for treating children with environmental enteric dysfunction. For their project, reported in the journal Science Translational Medicine, the group studied environmental enteric dysfunction in children living in Zambia and possible ways to treat it.
By GRACE CHAILE
FORMER First lady, Maureen Mwanawasa, has asked the Lusaka High Court to have the matter in which University of Lusaka Limited is demanding summary possession of her late husband, President Levy Mwanawasa’s retirement house, proceed to trial.
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A research team led by Professor Anskar Leung Yu-hung, from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified PLK4 as a novel therapeutic target for acute myeloid leukemia (AML) carrying the TP53 mutation. AML is a deadly disease, for which there is currently a lack of effective treatment options.
By LUCY PHIRI
LUSAKA Magistrate Kawama Mwamfuli has sent back a case involving Kamono Farms Initiative Ltd and its directors for re-allocation as she could not continue handling the matter.
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Stress during pregnancy is known to influence health outcomes, but a new study from Mass General Brigham researchers suggests that stress levels before pregnancy are also important to evaluate.