Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor’s microenvironment. Scientists at the German Cancer Research Center (DKFZ) and the Weizmann Institute in Israel have now shown that p53-mutated mouse breast cancer cells reprogram fat cells. The manipulated fat cells create an inflammatory microenvironment, impairing the immune response against the tumor and thus promoting cancer growth.
Attention-deficit/hyperactivity disorder (ADHD) often goes undiagnosed in adults—including parents—but it has a significant impact on family life.
We know the importance of staying hydrated, especially in hot weather. But even for something as simple as a drink of water, conflicting advice and urban myths abound.
Those trying to kick-start their weight loss or perhaps wanting to lose a few pounds before a big event or holiday may be tempted to try a crash diet. While it’s true that in order to lose weight you need to eat fewer calories than your body uses each day, in reality crash diets may actually work against you—and may make weight loss more difficult.
An AI model can predict which SARS-CoV-2 variants are likely to cause new waves of infection. Current models used to predict the dynamics of viral transmission do not predict variant-specific spread.
The pandemic has reached a “transition point,” the World Health Organization sais.
INSPECTOR General of Police Graphael Musamba is giving strange reasons on why the opposition parties should not be allowed to hold public rallies.
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An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice.
My friend Luke used to drink a pint of beer before a game of rugby. I don’t know whether he thought that it might reduce pain or improve performance, but the idea of taking drugs before “going into battle” goes back to the beginning of recorded history.
The average cost of providing care to hospitalized COVID-19 patients increased five times faster than the rate of medical inflation during the first two years of the pandemic, at least partly because of the application of additional medical technologies over the period, according to a new RAND Corporation study.