Posts in category: Uncategorized

Studying strange forms of RNA associated with the formation of aggregates in the brains of ALS patients could lead to new avenues for treatments.

How are memories consolidated during sleep? In 2021, researchers led by Dr. Thomas Schreiner, leader of the Emmy Noether junior research group at LMU’s Department of Psychology, had already shown there was a direct relationship between the emergence of certain sleep-related brain activity patterns and the reactivation of memory contents during sleep. However, it was still unclear whether these rhythms are orchestrated by a central pacemaker.

The Miles Sampa operation is a perfect recipe for political conflict and possible violence.

Researchers at the Center for Genomic Regulation in Barcelona, Spain, and the Wellcome Sanger Institute near Cambridge, UK, have comprehensively identified the allosteric control sites found in the protein KRAS. These are highly sought after targets for drug development, representing secret vulnerabilities that can be exploited to control the effects of one of the most important causes of cancer. The study presents the first complete control map for any protein and is published in the journal Nature.

Researchers have found an inexpensive tool that may help reduce rates of pneumonia for hospitalized patients—and it comes with bristles on one end.

Prenatal diagnosis of congenital heart defects—the most common birth defects in the United States—is associated with improved outcomes. Despite its importance, however, overall prevalence of prenatal diagnosis is low (12–50%).

Many ocular diseases involve changes in the structure and function of different regions of the back of the eye, also known as the “eye fundus.” For example, fluorescent pigments and tiny yellowish deposits called drusen accumulate under the retina in age-related macular degeneration, and the degeneration of neurons called ganglion cells is a defining characteristic of glaucoma.

Our body’s immune system is a complex network of organs, cells, and proteins that work in synchrony to protect our bodies against infections caused by pathogens and fight against disease-causing changes in our body, such as the emergence of cancer cells. Cell-mediated cytotoxicity is one of such defense mechanisms carried out by the immune system that fights against foreign cells.

The cost of severe flooding in the United States is often tallied in economic terms, including a flood’s impact on infrastructure.

SARS-CoV-2 variants are constantly emerging with a variety of changes in the conformation of the spike protein, resulting in alterations of virus entry mechanisms. Solely omicron variants use the endosomal clathrin-mediated entry.