New 3D co-cultured model to study effect of proton therapy on aggressive brain cancer

Researchers at TU Delft designed novel 3D-engineered scaffolds inspired by the geometry of the brain microvasculature. The micro-structures were co-cultured with both glioblastoma, an aggressive brain cancer, and endothelial cells, the building blocks of blood vessels. This model enabled researchers to study the effect of proton therapy on glioblastoma and uncover a possible protective role of endothelial cells on cancer cells.

COVID-19: The persistence of SARS-CoV-2 in the lungs and the role of innate immunity

One to two weeks after contracting COVID, the SARS-CoV-2 virus generally becomes undetectable in the upper respiratory tract. But does that mean that it is no longer present in the body? To find out, a team from the Institut Pasteur specialized in HIV, in collaboration with a French public research institute, the Alternative Energies and Atomic Energy Commission (CEA), conducted a study on lung cells in an animal model.

Study shows T cells can tackle new ‘Pirola’ SARS-CoV-2 variant

In August, researchers detected a new SARS-CoV-2 “variant of concern” in patients in Israel and Denmark. Since then, this variant, dubbed BA.2.86 or “Pirola,” has made its way around the globe. The Pirola variant has raised alarms because it is highly mutated. In fact, Pirola is as mutated as the omicron variant was, compared with the early SARS-CoV-2 variant included in the original vaccinations.

Researchers lay groundwork to study effects of maternal diabetes on fetal metabolism and development

UCLA scientists examined how exposure to higher levels of glucose alter fetal tissue metabolism, using a technique they pioneered to trace in utero carbon-13 in fetal tissues. Their paper, “Atlas of Fetal Metabolism During Mid-to-Late Gestation and Diabetic Pregnancy,” published in Cell, reveals the impact of maternal hyperglycemia on fetal tissues.

DPP apologises for failing to proceed with Malanji, Yamba case

By LUCY PHIRI

DIRECTOR of Public Prosecutions (DPP) Gilbert Phiri yesterday appeared before the Lusaka Magistrate Court to explain why the case involving former Foreign Affairs Minister, Joseph Malanji and former Secretary to the Treasury Fredson Yamba could not proceed before Senior Magistrate, Irene Wishimanga.

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