Using fertility preservation and/or assisted reproductive technologies (ART) did not adversely impact three-year cancer recurrence rates among patients with hormone receptor (HR)-positive breast cancer who paused endocrine therapy to become pregnant, according to results from the POSITIVE trial presented at the San Antonio Breast Cancer Symposium, held December 5–9, 2023.
Why do some older adults show declines in their spatial memory?
Aging becomes apparent in various ways, one of them being changes in memory function. But some older adults experience a faster decline in memory compared to others.
Large-scale DNA sequence resource reveals new regions of the human genome under natural selection
Every human’s genome has millions of genetic variants, but most have little to no effect, making it difficult for clinicians to make medical diagnoses based on genetic differences.
Researchers develop approach to study rare gene variant pairs that contribute to disease
Each gene in the human genome has two copies. When researchers detect two mutations within a particular gene in a patient’s genome, it can be difficult or expensive to determine if those two mutations are present in the same copy of the gene (“in cis”) or different copies of the gene (“in trans”).
Selective CDK2 inhibitor drug can stop cancer growth, animal study suggests
A new Peter Mac study using a pioneering drug has successfully controlled the growth of tumors and overcome existing drug resistance in multiple cancer types.
AI can identify women with high risk of breast cancer in screening examinations
The use of AI makes it possible for women with a high risk of breast cancer to be identified in mammography screening examinations so that the cancer can be caught earlier. An international research group led from Karolinska Institutet in Sweden has now shown that the method is effective in different European countries. The study is published in The Lancet Regional Health—Europe.
New insight on the role of the primate orbitofrontal cortex in value-based decision-making
The orbitofrontal cortex (OFC), a subsection of the brain’s frontal lobe, is known to play a part in value-based decision-making, the process of mentally weighing the outcome of different decisions and then selecting one. Value-based decisions include, for instance, choosing what to buy while shopping at a grocery store or deciding what apartment to rent among available options.
Strange DPP decision
THE justification proffered by the Director of Public Prosecution, Mr Gilbert Phiri, for stopping the prosecution of deranged Miles Sampa for forgery, misrepresentation and fraud is certainly not tenable at law. There is no such legal tenet.
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Cocoa extract supplement found to have benefits for cognition among older adults with lower diet quality
A study conducted by researchers, Dr. Chirag Vyas and Dr. Olivia I. Okereke at Massachusetts General Hospital, and Dr. Howard Sesso and Dr. JoAnn Manson at Brigham and Women’s Hospital has shown that cocoa extract has a potential protective effect on cognition but randomized clinical trials in older adults have had inconsistent results.
Why the presence of healthy cells enables cancer to resist treatment
Chemotherapy becomes less effective because healthy cells push cancer cells to grow more slowly, according to two studies from researchers at UCL and Yale.