Unraveling the age-related cellular changes in osteosarcoma progression

In a study published in the journal Genes & Diseases, scientists from Union Hospital, Tongji Medical College, and Huazhong University of Science and Technology delve into the molecular intricacies of osteosarcoma in the elderly. The team investigated senescent cells, cells that no longer divide or grow, and their influence on tumor progression. A spotlight was cast on methylmalonic acid (MMA), a compound found in elevated levels in the elderly, known to be associated with aggressive cancer characteristics.

YTHDF2’s role in promoting acute myeloid leukemia: The key lies in microRNA processing

In a study published in the journal Genes & Diseases, researchers from Beckman Research Institute of City of Hope, explored the impact of m6A modification on the maturation process of precursor microRNAs (pre-miRNAs) and its potential role in tumorigenesis. They have uncovered a novel mechanism behind the progression of acute myeloid leukemia (AML), a life-threatening blood cancer characterized by rapid expansion of abnormally differentiated hematopoietic cells.

Complications from flu largely preventable with annual flu vaccine

During National Influenza Vaccination Week (December 4-8, 2023), leading public health organizations are encouraging everyone to get a flu shot if they have not already done so. The flu is more than an inconvenience: it can lead to hospitalization, worsening of chronic medical conditions or even death. An annual flu vaccine is the best way to help prevent complications from the flu.

YWCA intensifies human rights campaign outreach 

By NATION REPORTER

THE Young Women Christian Association says there is need for enhanced sensitization on human rights to curb the abuse and violation of human rights by both men and women as the country continues to commemorate 16 days of gender activism.

YWCA National Council president Patricia Mubanga says both men and women need to know and respect each other’s right hence the need to enhance awareness on human rights.

Ms. Mubanga Says it is unfortunate that people have continued to violet human rights in all possible ways despite having laws in place.

She says it is about time that both men and women come in the open to report human rights violation in order to curb the vice.

Ms. Mubanga Has since appealed to all stakeholders including the church, traditional leaders, politician’s and government among others to come on board and enhance awareness on human rights.

‘Pharmacy Forecast’ identifies growing societal challenges expected to impact care

Societal issues—including the growth in ultra-high-cost treatments, the epidemic of mental health and substance use disorders, climate change, and the rise of artificial intelligence (AI)— could alter how health systems serve their communities within five years, according to the latest annual ASHP/ASHP Foundation Pharmacy Forecast Report. The 2024 Pharmacy Forecast, released at the ASHP Midyear Clinical Meeting & Exhibition, drew its findings from a survey of more than 250 pharmacy leaders from across the United States on key topics impacting health systems.

Mathematical dermatology: Unraveling the mechanism of urticaria from eruption shapes

The skin is the largest organ in the human body and plays an important role in maintaining homeostasis as well as protecting the body from the outside environment. Skin diseases can be life-threatening or heavily impair patients’ quality of life. Urticaria (also called “hives”) is common, affecting at least one in five people in their lifetime, and can persist for years or even decades.