A federal judge has stopped the Trump administration from cutting $11 billion in public health funding—at least for now.
Switching from dulaglutide to tirzepatide improves HbA1c reduction in type 2 diabetes
For patients with inadequately controlled type 2 diabetes receiving dulaglutide, switching to tirzepatide is associated with additional hemoglobin A1c (HbA1c) reduction and weight loss compared with escalating treatment with dulaglutide, according to a study published online April 4 in the Annals of Internal Medicine to coincide with the Internal Medicine Meeting, the annual meeting of the American College of Physicians, held from April 3 to 5 in New Orleans.
First step for pandemic prevention: Experts comment on WHO’s first binding national agreement
The World Health Organization (WHO) is on the verge of adopting the world’s first binding international agreement focused on pandemic prevention. This landmark development, schedule for potential ratification at the 78th World Health Assembly in May 2025, adopts a crucial One Health approach, emphasizing the global need to curb pandemic risks at the human-animal-environment interface. Dr. Raina Plowright, Rudolf J. and Katharine L. Steffen Professor of Veterinary Medicine, along with colleagues on The Lancet Commission on Prevention of Viral Spillover, published their comment piece on the agreement in The Lancet on April 3.
Pancreatic cells ‘remember’ cancer-linked epigenetic marks without mutations, study shows
Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic “marks” in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a temporary “memory” of those cancer-linked marks.
Serotonin functions as ‘prospective code for value’ in brain’s reward processing system
In our day-to-day lives, we’re constantly making a slew of decisions, from immediate matters to prospects on the far horizon. But the evolutionary nuts-and-bolts of how our brains weigh these numerous daily decisions and what role is played by the neurotransmitter serotonin has been shrouded in mystery.
Almost one in two Aussie teens have a chronic disease or developmental condition, says study
New research published today shows that almost half (45.6%) of Australian teens are living with chronic diseases or developmental conditions like attention deficit hyperactivity disorder (ADHD) or autism (ASD). The study has linked the conditions to unhealthy lifestyles, diets and poor mental health, prompting calls for further research and government action.
Planetary health diet and Mediterranean Diet associated with similar survival and sustainability benefits
Two plant-based diets were associated with similar survival benefits and low environmental impact, according to research presented at European Society of Cardiology (ESC) Preventive Cardiology 2025.
Alteplase increases frequency of functional independence after posterior circulation stroke
For patients with mainly mild posterior circulation ischemic stroke who do not receive thrombectomy, alteplase administered at 4.5 to 24 hours after onset results in higher frequency of functional independence at 90 days compared with standard medical care, according to a study published in the April 3 issue of the New England Journal of Medicine.
Preeclampsia associated with earlier onset and higher incidence of cardiovascular risk factors
Women who have experienced preeclampsia have accelerated accumulation of cardiovascular (CV) risk factors compared with women who had pregnancies without preeclampsia according to research presented at the European Society of Cardiology (ESC) Preventive Cardiology congress 2025.
Immune system’s age-related changes mapped with unprecedented detail
Why are older people more susceptible to infections than younger people? Why do vaccinations sometimes have less of an effect on them? In order to better understand the mechanisms of the aging immune system, the RESIST-Senior Individuals Cohort was set up as part of the Cluster of Excellence RESIST—a study with 550 citizens over the age of 60 and 100 younger participants aged between 20 and 40, all of whom come from the Hannover Region.