One main goal of anti-cancer therapies is to kill tumor cells without affecting the surrounding normal cells. Therefore, many drugs are designed to target tumor-specific antigens, which are molecules only expressed by cancer cells. However, it has proven difficult to identify such specific antigens in certain cancer types, including acute myeloid leukemia (AML).
Cervical artery dissection is a tear in an artery in the neck that provides blood flow to the brain. Such a tear can result in blood clots that cause stroke. A new study has found almost a five-fold increase in the number of U.S. hospitalizations for cervical artery dissection over a 15-year period.
Atopic dermatitis is an allergy affecting approximately 10% of the Japanese population, with symptoms closely related to social stress. In socially active adults, the disease often becomes chronic.
Nearly 16 million American adults have been diagnosed with attention deficit hyperactivity disorder (ADHD), but evidence suggests that more than 30% of them don’t respond well to stimulant medications like Ritalin and Adderall.
In Sweden, around 18,000 workers are exposed to hexavalent chromium in their workplace. Hexavalent chromium is a powerful carcinogen that is released, for example, during welding of stainless steel or the manufacture of paints and rustproofing.
A research team led by David C. Ayers, MD, has identified important factors in total knee replacement that predict outcomes five years after surgery.
Imagine a super-charged immune cell that can launch a focused attack on stubborn solid tumors—a smart fighter that destroys cancer cells for days without tiring. USC biomedical engineers have made this concept a reality, crafting what they have named the “EchoBack CAR T-cell,” which could soon be a game-changer in the field of cancer immunotherapy.
Comparing wealth and survival rates in the U.S. with those in Europe, researchers found that over a 10-year period, Americans across all wealth levels were more likely to die than their European counterparts.
A team of medical researchers and engineers at RSP Systems, in Denmark, working with a pair of colleagues from the Institute for Diabetes Technology, and another colleague with the University of Munich, both in Germany, has developed a Raman spectroscopy–based, noninvasive glucose monitoring (NIGM) system that has a much shorter calibration period than systems now in use.
The United States Cystic Fibrosis Foundation released the first guideline on newborn screening for cystic fibrosis (CF), in order to improve timely detection of CF in infants from all racial and ethnic backgrounds. The new guideline, based on systematic literature reviews and published in the International Journal of Neonatal Screening, reflects rigorous scientific investigation and perspectives from parents, CF specialists, public health representatives, primary care providers and genetic counselors.