An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks. With further development, the antibody might offer an effective drug treatment for those same breast cancers.
Improving deep sleep may prevent dementia, study finds
As little as 1% reduction in deep sleep per year for people over 60 years of age translates into a 27% increased risk of dementia, according to a study which suggests that enhancing or maintaining deep sleep, also known as slow wave sleep, in older years could stave off dementia.
Study links specific gut bacteria to increased risk of severe malaria
Indiana University School of Medicine researchers have identified multiple species of bacteria that, when present in the gut, are linked to an increased risk of developing severe malaria in humans and mice. Their findings, recently published in Nature Communications, could lead to the development of new approaches targeting gut bacteria to prevent severe malaria and associated deaths.
How a single synapse transmits both visual and subconscious information to the brain of fruit flies
Research led by Peking University, China, has discovered a single type of retinal photoreceptor cell in Drosophila (fruit fly) is involved in both visual perception and circadian photoentrainment by co-releasing histamine and acetylcholine at the first visual synapse.
Protein eIF4A emerges as a potential Achilles’ heel for triple-negative breast cancer
Improving treatments for triple-negative breast cancer (TNBC), an aggressive tumor with very poor prognosis and limited therapeutic targets, has been challenging. Responding to this need for better treatments, researchers at Baylor College of Medicine and collaborating institutions have investigated potential vulnerabilities in TNBC that could lead to novel therapies and improved outcomes for this devastating condition.
First ever gene therapy trial for children with Hunter syndrome opens
The UK regulatory authorities have approved the first ever trial of a revolutionary gene therapy for young children diagnosed with Hunter syndrome, a devastating rare lysosomal storage disorder.
Chilubi MP queries ZNS legal authority to run copper smelter
 By SHERRY CHABALA
CHILUBI Member of Parliament Mulenga Fube has challenged government to disclose the legal framework under which the Zambian National Service (ZNS) has been given the mandate to run the US$15 billion copper smelter to be constructed in North-Western Province.
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Study assesses impact of SARS-CoV-2 omicron subvariant BA.2.86’s multiple mutations
A combined team of medical researchers from Columbia University and the University of Michigan has found that, despite multiple mutations, the SARS-CoV-2 omicron subvariant BA.2.86 does not appear to be more dangerous than prior subvariants. In their paper published in the journal Nature, the group describes the multiple ways they tested the new subvariant and what they found by doing so.
New inflammatory mechanisms unveiled in the setting of liver disease and liver cancer
An international study involving Birmingham researchers identified for the first time how a protein found in the endothelium supports the transfer of specific immune cells, called macrophages, from the blood into the liver, causing inflammation—which can promote liver disease and liver cancer.
FDA approves mirikizumab, a promising induction and maintenance therapy for ulcerative colitis
The U.S. Food and Drug Administration (FDA) approved mirikizumab, on October 26, 2023, a highly effective new treatment for ulcerative colitis (UC), offering a new option to patients battling this chronic and debilitating inflammatory bowel disease.