A case study on ketamine reveals systemic barriers that prevent repurposing existing low-cost drugs like ketamine for treatment-resistant depression.
ESMO: PARP inhibitor plus immunotherapy lowers risk of endometrial cancer progression over chemotherapy alone
Immunotherapy with the anti-PD-L1 monoclonal antibody durvalumab improved progression-free survival (PFS) in patients with newly diagnosed advanced or recurrent endometrial cancer compared with chemotherapy alone, with further benefits gained from the addition of the PARP inhibitor olaparib in maintenance setting, according to researchers from The University of Texas MD Anderson Cancer Center.
Preventing collateral damage in cancer treatment
Using a simple concept and a patented Sandia sensor that detects radioactive materials, a team at Sandia National Laboratories has developed a patch to stop damage to healthy tissue during proton radiotherapy, one of the best tools to target certain cancerous tumors.
New care model delivers hepatitis C treatment to most vulnerable
Breakthrough treatments introduced over the last decade have transformed hepatitis C from a chronic and potentially deadly infectious disease into one that can be cured. But these medications have often been beyond the reach of those who are most vulnerable to the virus that causes it: people who inject drugs and lack stable housing.
Divisive democracy and constitutionalism
THE importance of our constitution as a fundamental framework for governance cannot be overstate. This doctrine simply means that Government power should be limited, structured and subjected to the rule of law.
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Researchers aim to streamline brain surgery with a new soft robotic system
Navigating the labyrinthine vasculature of the brain with standard surgical instruments can be incredibly challenging, even for the steadiest of hands. But with some robotic assistance, brain surgeons could potentially operate with far greater ease.
Q&A: The art of diabetes care—why precision medicine leads to better diabetes care
Diabetes can show up in almost anyone: pregnant women, babies, kids, teens, adults both young and old. But the condition’s various forms, all of which affect how the body processes blood sugar, can manifest quite differently in the hundreds of millions of people worldwide who have the disease—making it perfect for the individualized approach known as precision medicine, Stanford Medicine researchers say.
New large-scale study results add to evidence that vestibular loss increases dementia risk
Existing research shows a link between hearing loss and the risk of dementia, and a new study adds to growing evidence that vestibular loss can increase dementia risk as well. Results from this work, by a team from the Korea University College of Medicine, are published in Scientific Reports.
Probiotics delivered in biofilm state protect the intestines and brain in necrotizing enterocolitis model
Necrotizing enterocolitis (NEC) is a debilitating and deadly condition that affects infants who were born preterm. In NEC cases, intestinal tissues become inflamed, and in severe cases there is ischemia and death of the involved intestines. Treatment for NEC often involves surgery to remove the dying tissue.
Erdafitinib demonstrates improved responses in FGFR-altered advanced urinary tract cancers
Targeted treatment with the fibroblast growth factor receptor (FGFR) inhibitor erdafitinib improved responses and overall survival compared to standard chemotherapy for patients with metastatic urothelial cancers with FGFR alterations. Results from the Phase III THOR trial, led by researchers at The University of Texas MD Anderson Cancer Center, were reported at the 2023 European Society of Medical Oncology (ESMO) Congress.