Nearly 40% of patients diagnosed with type 2 diabetes imperil their health by stopping their medication within the first year, UVA Health diabetes experts note in a new paper highlighting a growing array of treatment options.
Higher cardiac deaths found in combined day-night heat waves
Cardiac deaths increase significantly during compound heat waves—heat waves where temperatures are elevated both during the day and overnight—according to a new study in Journal of the American College of Cardiology. The study also found that some types of heart disease are more sensitive to heat waves than others and that different types of heat waves may impact heart health in distinct, nonlinear ways.
Nanoparticles extend glioblastoma survival in phase one trial
Despite decades of research to develop effective treatments, the median survival for glioblastoma—the most common malignant primary brain tumor in adults—is just 15–18 months after diagnosis. One reason for this grim statistic is that these tumors invariably recur despite aggressive, multimodality treatments.
FDA’s top tobacco official is removed from post in latest blow to health agency’s leadership
The Food and Drug Administration’s chief tobacco regulator has been removed from his post amid sweeping cuts at the agency and across the federal health workforce handed down Tuesday, according to people familiar with the matter.
Layoffs begin at the nation’s health agencies
Employees across the massive U.S. Department of Health and Human Services began receiving notices of dismissal on Tuesday in a major overhaul expected to ultimately lay off up to 10,000 people. The notices just days after President Donald Trump moved to strip workers of their collective bargaining rights at HHS and other agencies throughout the government.
Dopamine neurons that fuel overeating may weaken effectiveness of obesity medication
Delicious and extremely palatable food can increase the tendency of hedonic eating, where one consumes food for the sole purpose of deriving pleasure instead of the body’s energy needs. Hedonic eating often leads to eating beyond satiety (fullness), which is linked to obesity. Although food palatability is closely linked to hedonic eating, the neural mechanisms underlying this process remain largely unclear.
GLP-1 drug use for weight loss has soared, costing billions
The number of Americans taking cutting-edge weight-loss drugs like Ozempic, Wegovy and Zepbound has skyrocketed in recent years, a new study says.
Study reveals stark racial disparities in IBD care across the United States
A study published in the American Journal of Gastroenterology reveals significant disparities in health care utilization among racial and ethnic groups with inflammatory bowel disease (IBD) in the United States. The research, led by investigators from the University of Pennsylvania, the University of North Carolina at Chapel Hill, and the Crohn’s & Colitis Foundation, provides crucial insights into the challenges faced by underrepresented communities in accessing and utilizing IBD care.
Low levels of a single enzyme influence pathway to malignancy in colorectal cancer, scientists find
The transformation of healthy cells into invasive colorectal tumors is an extraordinarily complex process involving numerous molecular mechanisms, according to cancer biologists in China who have discovered that low levels of a single enzyme strongly influence the pathway to malignancy.
Proteomics and chicken eggs: A novel path to match young cancer patients with the right drugs
A pan-Canadian team has developed a new way to quickly find personalized treatments for young cancer patients, by growing their tumors in chicken eggs and analyzing their proteins.