Posts in category: Uncategorized

Researchers have generated induced pluripotent stem cell (iPSC)-derived kidney organoids to model Alport syndrome caused by a mutation in the COL4A5 gene and have demonstrated the utility of a chemical chaperone to rescue the protein misfolding and collagen misassembling caused by the mutation. The research is published in the journal Communications Biology.

…as Zambia humiliate the Cranes of Uganda 

By MICHAEL MIYOBA 

LEICESTER City striker Patson Daka impressed with a brace as Zambia bounced back from the painful 1-0 defeat to Egypt by beating Uganda 3-0 in the second match of the back to back international friendly matches played at the at Al-Hamriya Sports Club Stadium in the United Arab Emirates (UAE).

Fashion Sakala grabbed the other goal as the Chipolopolo outshined the Cranes of Uganda to pick the crucial win.

Chipolopolo coach Avram Grant, who was seeking redemption after the loss to Egypt which was his first as national team coach had made some changes to his starting lineup.

Grant gave Golden Mafwenta, Zephenia Phiri and Edward Chilufya the opportunity to start while captain Lubambo Musonda, Kelvin Kapumbu and right back Benedict Chepeshi were relegated to the bench.

The Chipolopolo boys dominated play from the first whistle and it only took six minutes for Daka to put Zambia ahead after he converted a penalty won when Klings Kangwa was fouled in the box.

Sakala came close to doubling the lead but was unlucky as he missed after he was perfectly set up by Phiri in the 14th minute.

Uganda’s first dangerous opportunity to level matters came four minutes before the half hour mark when Ibrahim Juma tried his luck from a free kick which Francis Mwansa collected with ease. 

Two minutes before the hour mark, Rodrick Kabwe who was trusted with the captain’s arm band in the absence of Musonda could have doubled Zambia’s lead with a free kick which he sent way over the bar.

Simba SC star midfielder, Cletus Chama was introduced in the 60th minute for Mafwenta and immediately made a positive impact as he contributed to a move which resulted in Zambia’s second goal through Sakala. 

Sakala rose high to head Phiri’s perfect cross from the right.

Uganda tried to make some changes with the introduction of Usama Abdu for Kizza Kayondo while, Kasim Mato replace Basangwa Richard. Laban Tibita came in for Khalid Aucho.

The changes couldn’t inspire a comeback as Daka completed his brace in the 69th minute by nodding the ball into the back of the net after benefiting from another perfect cross from Phiri.

With about 18 minutes before the last whistle, Grant withdrew Sakala and Daka for Kelvin Kapumbu and Rally Bwalya.

The Chipolopolo held on to pick their fourth win under the former Ghana and Chelsea FC tutor who has one draw, four wins and one defeat. 

Glioblastoma (GBM), an aggressive brain cancer, is notoriously resistant to treatment, with recurrent GBM associated with survival of less than 10 months. Immunotherapies, which mobilize the body’s immune defenses against a cancer, have not been effective for GBM, in part because the tumor’s surrounding environment is largely impenetrable to assaults from the body’s immune system.

Starting buprenorphine treatment for opioid use disorder through telehealth was associated with an increased likelihood of staying in treatment longer compared to starting treatment in a non-telehealth setting, according to a new study analyzing Medicaid data from 2019–2020 in Kentucky and Ohio.

A vaccine designed to protect against three different deadly coronaviruses shows success in mouse studies, demonstrating the viability of a pan-coronavirus vaccine developed by researchers at the Duke Human Vaccine Institute.

Investigators from the Smidt Heart Institute at Cedars-Sinai found that an artificial intelligence (AI) algorithm can detect an abnormal heart rhythm in people not yet showing symptoms.

A growing body of research is drawing attention to health threats posed by human-made chemicals called “forever chemicals,” which are targeted by a new California law requiring manufacturers to reduce their use in food packaging and cookware.

Women are nearly twice as likely as men to be diagnosed with an anxiety disorder, but among boys and girls the likelihood is the same. New University of California, Davis, research has identified changes in the brain during puberty that may account for differences in how women and men respond to stress.

By NATION REPORTER

POLICE in Lusaka have arrested two Ministry of Health officials based at the University Teaching Hospitals (UTH) for Theft by Public Servant.

A new study from UNSW Sydney shows that teenagers with OCD experience deficits in decision making and behavioral control. This is linked to abnormal activity in an area of the brain called the orbitofrontal cortex (OFC). The research is published this week in Biological Psychiatry Global Open Science.