MYC inhibition in melanoma: Preclinical promise and the unveiling of a prognostic gene signature

Cutaneous melanoma, the most aggressive form of skin cancer, is the fifth most diagnosed cancer in Europe and one of the most frequent causes of cancer death, with incidence and mortality trends on the rise. While the development of more effective treatments including immune-based approaches have improved survival in some patients, many do not benefit from these anti-cancer therapies due to intrinsic or acquired drug resistance.

Haptics-enhanced virtual reality can boost learning in dental education

Combining VR haptics with conventional tooth preparation exercises in dental education, it is possible to improve students’ learning outcomes, according to a new study carried out at the Institute of Dentistry, University of Eastern Finland. In addition, students felt that their self-confidence improved after practicing in the VR haptic environment. The results were presented at the AMEF conference 2023 in Helsinki.

New drug may help prevent migraine for difficult cases

The drug atogepant may help prevent migraines for people who have had no success with other preventive drugs, according to a preliminary study released April 20, 2023, which will be presented at the American Academy of Neurology’s 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023. The study involved people with episodic migraine, which is defined as having up to 14 headache days per month with migraine characteristics.

Invest your NAPSA partial withdraw – PIA 

By BUUMBA CHIMBULU

The Pensions and Insurance Authority (PIA) has implored people accessing funds through the partial withdraw from the National Pension Scheme Authority (NAPSA) to re-invest the money into projects with proper returns.

And the authority has encouraged employees to take keen interest in ensuring that their employers remit the funds to NAPSA for them to be able to access the benefits.

President Hakainde Hichilema on Monday this week signed into law the NAPSA Amendment Bill 2023 which allows for the partial withdraw of pensions.

Commenting on the development, PIA acting Registrar, Namakau Ntini, people accessing these funds should ensure they adequately prepare by re-investing in bankable projects with returns which would earn them more money going forward.Ms Ntini explained that the funds from NAPSA were meant for long-term benefits, hence the need to ensure they were not misused.

She said this at a media workshop in Lusaka yesterday held under the theme “The Role of Media in Enhancing Public Understanding and Appreciation of Pensions and Insurance.”

“Now we have NAPSA that is able to allow a access to pensions savings. I am sure you have seen what has been going around social media where people are literally saying can I buy a jet or upgrade myself, but if you really listened carefully to what the President said, these funds are supposed to be re-invested.

TRACY KAKUSA: NEXT BIG THING IN GOSPEL MUSIC INDUSTRY

By TROY MUKUPA

“God rewrites stories and He can use anyone as a vessel regardless of what you or other people think,” says talented Chingola-based gospel singer and songwriter Tracy Kakusa in an interview.

Speaking to the Daily Nation Lifestyle, Friday, after the successful release of “Messiah” a brand new joint on which she collaborated with the talented Alinedi, Tracy said the single was an introduction to the many musical projects she has lined up for 2023.

Born on 22 February from Mrs. Theresa Mukuma Kakusa and the late Mr. Justin D’jango Kakusa, Tracy a graduate from the Copperbelt University and currently pursuing her masters (BSc Production and Operations Management, MBA in project management) gained recognition after the successful release of her two hit singles, “Eko Ali” and “He chose me” which has 2 versions: one in which she featured Likezo and another in which she featured Jubilant.

Tracy Kakusa

“The ‘Eko Ali’ song mainly talks about seeking God in our dire moments with an assurance that Ge will be found. Even when situations are hard, we need to hold onto Him and that He will answer us. Jeremiah 29:13 says; “You will seek Me and find Me when you search for Me with all your heart”. He Chose Me song is a reminder to the listener that God can use anyone, that God rewrites stories and He can use you as a vessel regardless of what you or other people think as written in Jeremiah 1:5 which reminds us that before God formed any of us in the womb, He knew you and me, and before we were born He set us apart”

“Messiah, the one we just released is a celebrational song. I did this one as a duo collaboration with Alinedi. The song is all about thanking God, Almight, for His goodness. This is a song that has a message of reminding the listener that God is good all the time as He is the same today, tomorrow and the days to come,” she added

With catch verses in this new release “Messiah”, it’s clear Tracy Kakusa aspires to be a force in the gospel music industry as she continues to offload more sought after songs.

The world of diabetes brought to life on a diminutive chip

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia associated with diabetes is not only inherently dangerous, but it also can lead to various complications, raising serious concerns. Diabetes may be generally categorized as either type 1 (T1D), which arises from defects in insulin-secreting cells that result in the absence of insulin production, and type 2 (T2D), which stems from reduced insulin secretion due to unhealthy lifestyle habits such as poor diet and lack of exercise.