Posts in category: Uncategorized

Most people think of dementia as something that affects a person’s brain. But a new study shows just how much damage it does to a person’s wallet and bank account too—as well as the higher demands it places on their family members.

Much evidence exists to show that in humans, oral inflammatory conditions such as periodontal disease can affect overall health. In its later stages, periodontal disease can lead to systemic issues such as cancer, cardiovascular disease, and diabetes. Until now, however, little has been known about how it might affect healthy oral tissue.

Microtia is a congenital disorder that can occur as a malformation of the external ear in children. In a new study published in Science Advances, Dominika Zielinska and a research team in tissue biological research, tissue engineering, polymer technologies and biofabrication at the University of Children’s Hospital Zurich, ETH Zurich, Switzerland and the U.S., developed a tissue-engineered treatment approach by using bioprinted autologous auricular cartilage construct as ear cartilage, combined with a bioengineered human pigmented and prevascularized ear skin substrate already tested in immunocompromised rats.

Cancer research has long focused on targeting the genetic mutations that drive tumors. Many of these genetic changes affect genes that allow mutated cells to replicate out of control. While developing drugs to target these mutations can benefit some patients, most tumors either lack targetable mutations or develop resistance to those therapies as a result of the accumulation of even more mutations.

Research published in Neuropsychopharmacology by a team of researchers at the University of Wollongong (UOW), National Institute of Complementary Medicine Health Research Institute and Neuroscience Research Australia has found molecular evidence highlighting important sex differences in the brains of people with major depressive disorder, with evidence of changes occurring specifically in the female brain, but not in males. The paper is titled “Sex- and suicide-specific alterations in the kynurenine pathway in the anterior cingulate cortex in major depression.”

New research has identified significant variations in the gut microbiome of individuals who developed pre-cancerous colonic lesions, suggesting a potential connection between gut bacteria and the onset of colorectal lesions and cancers. These findings, presented at UEG Week 2023, open promising new avenues for enhancing the detection and prevention of colorectal cancer.

By MICHAEL MIYOBA

CHIPOLOPOLO striker Fransisco Mwepu says he is determined to work hard to replicate his club form at the senior national team. 

Mwepu is part of the 25-member squad which is in the United Arab Emirates (UAE) for the back-to-back international friendly matches against Egypt and Uganda.

The former Under-20 star who features for Spanish club Atlético Sanluqueño CF came in as a second half substitute as Zambia lost the first international friendly match in the UAE 1-0 to North African giants Egypt.

Mwepu, the young brother to former Chipolopolo captain Enock Mwepu scored six goals in seven matches for Atlético Sanluqueño CF to catch the eye of Chipolopolo coach Avram Grant who will be leading Zambia in their final friendly match against Uganda tomorrow.

“It’s a privilege, these are big games and to represent the nation its always a pleasure for me so I’m very happy to be here. I just want to work hard also and do my best and add one or two things to the team to ensure that it also moves forward,” Mwepu said.

“I’m doing well at my club and I also hope that I can help the national team to score goals, as a striker its always important to score goals and I hope to replicate that at the national team,” he said.

On how he felt after featuring in the game against Egypt on October 12, Mwepu said; “It is a good feeling for me. Those are high games and competition is always high so I’m very happy to add value to the team and contribute one or two things.”

Mwepu said the Chipolopolo boys will have to give their best against Uganda to bounce back from the loss to Egypt.

“There are no small games when playing for the national team so against Uganda, it’s a tough game, a good friendly game so we just have to give our best and put in our level best and I’m also looking forward to play the game and see how it will be,” Mwepu said.

Mwepu said the friendlies in UAE would play a key role to ensure that the Chipolopolo boys prepare for both the World Cup qualifiers scheduled to start in November and the delayed 2023 Africa Cup of Nations slated for January 2024 in Ivory Coast.

After 12 initial weeks of weight loss with intensive lifestyle intervention alone, participants in the SURMOUNT-3 study who were randomly assigned to tirzepatide for 72 weeks achieved a total mean reduction in baseline body weight of 24.3% at week 84.

An overwhelming majority of adults (93%) recognize a lump as a symptom of breast cancer, but less than half recognize other common symptoms associated with the disease, according to a consumer survey commissioned by The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James).

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide, with a 5-year survival rate of less than 10%. Many PDAC tumors in early stage go undetected because they are not found using conventional imaging methods, including fluorodeoxyglucose positron emission tomography (PET) scans. To more efficiently combat this cancer, a team led by researchers at Osaka University is combining diagnostic and therapeutic procedures into a single integrated process: theranostics.