Researchers shed light on protein’s role in lactation as well as breast cancer

Milk production in mammals is a crucial process for the organism, perfected along the course of evolution. It is regulated by sophisticated molecular mechanisms still under investigation. A new study published in Nature Communications comes a step closer towards understanding them, as it delves into the role of a protein, called RANK, which is essential for the functionality of mammary glands, and is also key in breast cancer.

Forxiga trial shows clinically meaningful improvements in glycemic control among patients aged 10–17 years

Positive results from the T2NOW Phase III trial demonstrated significant reduction in A1C, a marker of average blood sugar, for patients treated with Forxiga (dapagliflozin) compared with patients receiving placebo. Adjusted mean change in A1C was −0.62% for Forxiga versus +0.41% for placebo, a difference of −1.03% (95% CI: -1.57-0.49; p