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At two years of follow-up, patients with a poorly functioning tricuspid valve in the heart who received the best available medical therapy plus a minimally invasive procedure using a clip to repair the valve were 28% less likely to be hospitalized for recurrent heart failure than similar patients who were initially randomly assigned to medical therapy alone. The study was presented at the American College of Cardiology’s Annual Scientific Session (ACC.25) on March 30 in Chicago. The study was simultaneously published online in Circulation.

Among patients with uncontrolled hypertension, the investigational drug lorundrostat brought a significant reduction in blood pressure at 12 weeks compared with placebo, according to a study presented at the American College of Cardiology’s Annual Scientific Session (ACC.25).

Compared with standard medical care, early use of a temporary intra-aortic balloon pump (IABP) to support heart function in patients who were critically ill with cardiogenic shock caused by heart failure did not improve 60-day survival or enable more patients to successfully transition to long-term treatment, according to featured clinical research presented at the American College of Cardiology’s Annual Scientific Session (ACC.25) and simultaneously published in JACC. The trial was stopped early when an independent monitoring group of physicians concluded that the device offered patients no additional benefit.

When a critically injured patient is admitted to the hospital, how much supplemental oxygen should they receive? Research published in JAMA Network Open led by investigators at the University of Colorado School of Medicine suggests it’s often less than the current standard.

The Tobacco Control Research Group (TCRG) at the University of Bath has published the first study examining tobacco and nicotine industry submissions on the 2023/24 Tobacco and Vapes Bill, introduced by the Conservative government. The Bill proposed banning tobacco sales to anyone born after 2009 and tightening regulations on nicotine products, including e-cigarettes. The Bill was later updated in 2024/25 by the current government.

Since the COVID-19 pandemic, when much of medical education shifted from in-person to virtual settings, Yale School of Medicine (YSM) researchers have sought to understand how virtual learning environments impact medical student learning.

Marking a breakthrough in the field of brain-computer interfaces (BCIs), a team of researchers from UC Berkeley and UC San Francisco has unlocked a way to restore naturalistic speech for people with severe paralysis.

Excessive sodium consumption can worsen high blood pressure, which is linked to cardiovascular disease, which in turn is responsible for 20 million deaths a year globally.

People with heart failure have long been advised to limit the amount of fluids they consume each day to help reduce congestion, or the buildup of fluid in the lungs and extremities, but that advice provides no benefit, according to a study presented at the American College of Cardiology’s Annual Scientific Session (ACC.25) on March 30 in Chicago.

Patients with severe aortic stenosis at low surgical risk who underwent supra-annular, self-expanding Evolut transcatheter aortic valve replacement (TAVR) had similar rates of death or disabling stroke at five years compared with those whose valves were replaced through standard open heart surgery, based on new follow-up data from the Evolut Low Risk trial presented at the American College of Cardiology’s Annual Scientific Session (ACC.25) on March 30 in Chicago.