New tests of a recently approved vaccine for respiratory syncytial virus—RSV—show the shot remains effective against a range of variants producing potent antibody responses against current and past strains, and may even bode well against future viral offshoots.
Targeting autophagy to enhance memory immune responses
Memory B cells depend on autophagy for their survival, but the protein Rubicon is thought to hinder this process. Researchers from Osaka University have discovered a shorter isoform of Rubicon called RUBCN100, which enhances autophagy in B cells. Mice that lacked the longer isoform, RUBCN130, produced more memory B cells in a way that relied on autophagy. These findings provide further insight into the role of Rubicon in autophagy.
Food insecurity for children in Indigenous communities is a crisis that needs to be addressed, researchers say
Dr. Anna Banerji’s ties to the Arctic run deep. She visited for the first time in 1995 to research respiratory syncytial virus (RSV) in Inuit babies. In 2004, she adopted an Inuit son and developed a close relationship with his foster and biological families. As a tropical disease specialist, infectious disease physician and pediatrician, she was originally looking into RSV vaccine access, but over time and more than 50 visits, another glaring issue in Northern communities became obvious: the lack of food security so many families—and particularly children—face.
Study evaluates protein that regulates pigment cell development for role in skin cancer
The microphthalmia-associated transcription factor (MITF) is the master regulator of pigment cell development and, as a lineage survival oncogene, plays a crucial role in the skin cancer melanoma and its resistance to therapy. How MITF distinguishes between its seemingly incompatible differentiation and proliferation-associated targets in the genome has been a bit of a puzzle.
Researchers identify structure in circadian mRNA that affects the sleep-wake cycle
Circadian rhythms, the internal biological clocks that regulate our daily activities, are essential for maintaining health and well-being. While the role of transcription in these rhythms is well-established, a new study sheds light on the critical importance of post-transcriptional processes.
How the hippocampus distinguishes true and false memories
Let’s say you typically eat eggs for breakfast but were running late and ate cereal. As you crunched on a spoonful of Raisin Bran, other contextual similarities remained: You ate at the same table, at the same time, preparing to go to the same job. When someone asks later what you had for breakfast, you incorrectly remember eating eggs.
POWER, MUZA OUT
By MICHAEL MIYOBA
ZAMBIAN Champions Power Dynamos have been eliminated form the CAF Champions League after a 3-3 aggregate stalemate against Tanzanian champions Simba Sports Club who were fortunate to march on to the group stage thanks to an away goal rule.
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Govt. calls for urgent formulation of policies for clean energy
NORTH-WESTERN Province Permanent Secretary Grandson Katambi has called for the urgent formulation of policies that will ensure all financial investments in Zambia promote agroecology and clean energy.
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Drew Weissman, Nobel-winning mRNA pioneer
Drew Weissman’s decades of research into mRNA technology paved the way for COVID-19 vaccines, finally earning a Nobel prize for the physician-scientist.
Precision medicine navigators increase genomic testing rates for Black patients with prostate cancer
The presence of a clinical navigator to act as a liaison between people with prostate cancer and the health care system greatly increases the likelihood that patients, especially Black patients, will receive advanced testing that can help predict the severity of their disease and guide treatment, a new study suggests.